Protein Alignment Nmdar2 and Ir68a

DIOPT Version :10

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Alignment Length: 858
• Identity: 168/858 - (19%)
• Similarity: 291/858 - (33%)
• Gaps: 292/858 - (34%)

  Fly   198 FLQLAGYLGIPV-ISWNADNSGLERRASQSTLQLQLAPSIEHQSAAMLSILERYKW-----HQFS 256
            |:.||....||: |:..|..||.|       :||::             :|::..|     ..|:
  Fly    11 FISLAMATSIPIPIANPAPLSGYE-------MQLKI-------------LLQKILWVANVKRCFA 55

  Fly   257 VVTSQIAGHDDFVQAVRERVAEMQEHFKFTILNSIV---VTRTSDLMELVNSEARVMLLYAT--- 315
            |:|      ||....:.:|:      |..::...::   |.||::..:|.....:|.|....
  Fly    56 VIT------DDLHYPIYDRI------FFESVGRRVIPFFVMRTNESDDLQRPSRQVELFVKAIKS 108

  Fly   316 ---QTEAITILRAAEEMKLTGENYVWVVSQSVIEKKDAHSQFPVGMLGVHFDTSSA------ALM 371
               :...||||..            |.|.:               .||..:|..|.      .|:
  Fly   109 SDCELNVITILNG------------WQVQR---------------FLGYIYDNRSLNMQKKFVLL 146

  Fly   372 NEI----SNAIKIYSYGVEAY--------------LTDPANRDRRLTTQSLSCEDEGRGRWDNGE 418
            :::    |:.|.::|..::|.              :..|......|..::::..:.|:|.  ||.
  Fly   147 HDLRLFESDMIHLWSVFIDAIFLKRQLDNKYTISTIAFPGILSGVLVMKNIANWELGKGL--NGR 209

  Fly   419 IFF----KYLRNVSIEGDLNK--PNIEF-TADGDLRSAELKIMNLRPSANNKNLVWEEIGVWKSW 476
            |.|    ..|...|:...:::  |.:.: .|....:..|::|||....|.|...|:     :|..
  Fly   210 ILFADKTSNLFGTSLPVAISEHVPMVLWANATKSFQGVEVEIMNALGKALNFKPVY-----YKPN 269

  Fly   477 ETQKLDIRDIAWP----GNSHAPPQGVPEKFHLKITFLEEAPYINLSPADPVSGKCLMDRGVLCR 537
            :|:.:|     |.    |.|.|...|.|:.:....|.::               ..|:|     .
  Fly   270 QTENMD-----WTELDGGASVAYGSGNPDGYAQNGTHID---------------SMLVD-----E 309

  Fly   538 VAADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTYELVRV------EDGKWGT-- 594
            |||.   :|...:|..|..:.:        :.|:|..|..   .:|.:..      .|..|.|
  Fly   310 VAAH---SARFAIGDLHLFQVY--------LKLVELSAPH---NFECLTFLTPESSTDNSWQTFI 360

  Fly   595 --LENGKWNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISPTAFL 657
              ...|.|.|            ||.||.:    ...|.::..|:.   ||:    .|.:|...|.
  Fly   361 LPFSAGMWVG------------VLLSLFV----VGTVFYAISFLN---AII----NGNVSSEFFR 402

  Fly   658 -------EPFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDM--KLYLQNTNVTPYRFSLFRTY 713
                   .|.|...:..:        :|.|.:..:.|..|..|  .|:...||.....:|:
  Fly   403 CLRPNRNVPMDPKIYRRI--------SFRIAISRYRSSKGDRMPRDLFDGYTNCILLTYSM---- 455

  Fly   714 WLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRL 778
                 :|:.|...:  ||.:..|.:|..:.::.::.:|.|.|:..|.:...........|.|...
  Fly   456 -----LLYVALPRM--PRNWPLRVLTGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDLLR 513

  Fly   779 VHPFSHKPSFKFGTIPYSHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTV- 842
            .|            ||.| |.:|.::.|.:..|           |.||..:...::.|.|...:
  Fly   514 SH------------IPPS-TGATENRQFFLEAN-----------DEVARKVGEKMEVFGYSDDLT 554

  Fly   843 ----------------LDYLVAQDE---------DCRL-MTVGSWYAMTGYGLAFSRNSKYVQMF 881
                            |.||...||         :|.| |.|         .||..:||
  Fly   555 SRIAKGQCAYYDNEFYLRYLRVADESGSALHIMKECVLYMPV---------VLAMEKNS------ 604

  Fly   882 NKRLLEFRANGDLERLRRYWMTGTCRPGKQEHKSSDPLA-------LEQFLSAFLLLMAGILLAA 939
               .|:.|.:..::.|....:.........||..::.||       :::|.|:|:.|:.|.:::.
  Fly   605 ---ALKPRVDASIQHLAEGGLIAKWLKDAIEHLPAEALAQQEALMNIQKFWSSFVALLIGYVISM 666

  Fly   940 LLLLLEHVYFKYI 952
            |.||.|..:||:|
  Fly   667 LTLLAERWHFKHI 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..485	CDD:380601	64/332 (19%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	82/451 (18%)
Ir68a	NP_648455.2	Lig_chan	367..661	CDD:459656	73/377 (19%)