Protein Alignment Nmdar2 and Ir64a

DIOPT Version :9

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Alignment Length: 753
• Identity: 132/753 - (17%)
• Similarity: 235/753 - (31%)
• Gaps: 250/753 - (33%)

  Fly   373 EISNAIKIYSYGVEAY----LTDPANRDRRLTTQSLSCEDEGRGRWDNGEIFFKYLRNVSIEGDL 433
            |:::|..:||   |.:    :.|.|...|..|.       ||.|:.|:||:            :.
  Fly   171 ELASAKMLYS---EKFHWLLIEDFAWHGRTQTA-------EGSGKRDDGEM------------EE 213

  Fly   434 NKP---NIEFTADGDLRSAE--LKIMNLRPSANNKNLVWEEIGVWKSW-ETQKLDIRDIAWPG-- 490
            .:|   .|:.|.|.||.|.|  |..|||..:.        |:.:.|.. |.....:.|:..||
  Fly   214 EEPPGQQIQATDDEDLPSIESFLGGMNLYMNT--------ELTLAKRMSEAAHYTLFDVWNPGLN 270

  Fly   491 ----------NSHAPPQGVPEKFHLKITFLEEAPYINLSPADPVSGKCLMDRGVLCRVAADHEMA 545
                      .|..|.:|:    .|...|...:.............:|::       |..:..|.
  Fly   271 YGGHVNLTEIGSFTPTEGI----QLHTWFRTTSTVRRRMDMQHARVRCMV-------VVTNKNMT 324

  Fly   546 ADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLENGKWNGLIADLVNR 610
            ..:.....|.........:.|..:||....:...:|:.|.|..  .||.::||:::|:|..|:..
  Fly   325 GTLMYYLTHTMSGHIDTMNRFNFNLLMAVRDMFNWTFVLSRTT--SWGYVKNGRFDGMIGALIRN 387

  Fly   611 KTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISP--------------TAFLEPFD 661
            :||:....:....||...:|             ||.|:....|              ..||:||.
  Fly   388 ETDIGGAPIFYWLERHKWID-------------VAGRSWSSRPCFIFRHPRSTQKDRIVFLQPFT 439

  Fly   662 TASWMLV---GIVAIQAATFMIFLFEW----------LSPSG----------------------- 690
            ...|:|:   |::.:....|:..: ||          :.|.|
  Fly   440 NDVWILIVGCGVLTVFILWFLTTI-EWKLVPHDGSALIKPKGGAPPRHHYQQQQQQEQVEAPVRP 503

  Fly   691 -------------------YD-----------------MKLYLQNTNV----TPYRFSLFRTYWL 715
                               |:                 :..|:::...    .|.|..||
  Fly   504 ITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKKAPERVGLF----- 563

  Fly   716 VWAVLFQAAVHVDSPRGFTSRFMTN-----VWALFAVVFLAIYTANLAAFMITREEFHEFSGLND 775
            :.:|||...:......||::.|::.     ...||:......|:|::...:: .|:......|:|
  Fly   564 LESVLFFVGIICQQGLGFSTSFVSGRCIVITSLLFSFCIYQFYSASIVGTLL-MEKPKTIKTLSD 627

  Fly   776 SRLVH-----------------------------------------------------PFSHKPS 787
              |||                                                     |.|..|:
  Fly   628 --LVHSSLKVGMEDILYNRDYFLHTKDPVSMELYAKKITSVPTTKENEADEDEPVDPNPVSTDPA 690

  Fly   788 FKFGTIPYSHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTVLDYLVAQ--- 849
            ..:..|.:|| ::..|...|...|::         |....:|.....:|..|......::|:
  Fly   691 KSYRDIVHSH-ETGAHAKDNAASNWL---------DPETGLLRHLGFAFHVDVAAAYKIIAETFS 745

  Fly   850 DED-CRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYWMTGTCRPGKQEH 913
            ::| |.|..|..:.......: ..:||...::.:..|......|.|......|.:......|:..
  Fly   746 EQDICDLTEVSMFPPQKTVSI-MQKNSPMRKVISYGLRRVTETGILTYHFNVWHSRKPPCVKKIE 809

  Fly   914 KSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVYFKY 951
            .|...:.::...||.|:|:....:..::|..|.:|.|:
  Fly   810 TSDLHVDMDTVSSALLILLFSYAITLMILGTEILYSKW 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373	31/126 (25%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	86/557 (15%)
		Lig_chan	665..928	CDD:278489	57/400 (14%)
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	27/129 (21%)
		Lig_chan	563..828	CDD:278489	46/283 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462956
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840