DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nmdar2 and Ir7g

DIOPT Version :9

Sequence 1:	NP_001014714.1	Gene:	Nmdar2 / 31107	FlyBaseID:	FBgn0053513	Length:	1083	Species:	Drosophila melanogaster
Sequence 2:	NP_001368933.1	Gene:	Ir7g / 31694	FlyBaseID:	FBgn0029968	Length:	607	Species:	Drosophila melanogaster

Alignment Length:	295	Identity:	64/295 - (21%)
Similarity:	102/295 - (34%)	Gaps:	89/295 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 NIGLIAPHTNFGKREYLRSINNAVTGLTKTRGAKLTFLKDYSFEQKNIHFDMMSLTPSPTAILST 166
            |:..:.||           .:|.|.|........||.|:.:||               |...|:.
  Fly   299 NLTPVFPH-----------YSNRVVGCLLLNAHNLTSLEIWSF---------------PFQALTW 337

  Fly   167 LCK--EFLRVNVSAILYMMNNEQFGHSTASAQYFLQLAGY---LGIPVISWNADNSGLERRASQS 226
            :|.  .||.::..|:|: ..        |..:..|.||.|   ||:|:           ....:.
  Fly   338 ICLVFSFLSISCLALLHXRG--------AGDRLALVLAVYAASLGLPI-----------DPPERP 383

  Fly   227 TLQLQLAP------SIEHQSAAMLSILERYKWHQFSVVTSQIAGHDDF--------VQAVRERVA 277
            :|||..|.      .:....:|:|..:.||..||......|...|.|:        :|.:|| |.
  Fly   384 SLQLLFASWLIFGLIVRSMYSALLFFILRYHLHQRLPGNLQDLTHGDYAAVMGRTTLQDLRE-VP 447

  Fly   278 EMQEHFKFTILNSIVVT--------RTSDLMELVNSEARVMLLYATQTEAITILRAAEEMKLTGE 334
            .:|:   ...|.|::||        ||.|...|........|.:...::. .:|...:.....|.
  Fly   448 SLQD---LLGLKSVIVTSEREEEVLRTLDRCTLREGAGSHPLFFGLISQD-ALLHLTQRGHRAGA 508

  Fly   335 NYVWVVSQSVIEKKDA-----HSQFPVGMLGVHFD 364
            .:  ::.|.|:|::.|     ||.     |..|.|
  Fly   509 YH--IIPQDVLEQQLAIYLQKHSH-----LASHLD 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373	64/295 (22%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436
		Lig_chan	665..928	CDD:278489
Ir7g	NP_001368933.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463024
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840