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Protein Alignment Nmdar2 and Gria2

DIOPT Version :9

Sequence 1:	NP_001014714.1	Gene:	Nmdar2 / 31107	FlyBaseID:	FBgn0053513	Length:	1083	Species:	Drosophila melanogaster
Sequence 2:	NP_001077280.1	Gene:	Gria2 / 29627	RGDID:	61862	Length:	883	Species:	Rattus norvegicus

Alignment Length:	983	Identity:	231/983 - (23%)
Similarity:	387/983 - (39%)	Gaps:	246/983 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 ISLLLLTVLTLLILDTRSCQGLRLTNGGGSLSKGAAANKEQLNIGLIAPHTNFGKREYLRSINNA 124
            ||:||..||..||... |...:::   ||...:||........:|::    .|...|:
  Rat     7 ISVLLSPVLWGLIFGV-SSNSIQI---GGLFPRGADQEYSAFRVGMV----QFSTSEF------- 56

  Fly   125 VTGLTKTRGAKLTFLKDYSFEQKNIHFDMMSLTPSPTAILSTLCKEFLRVNVSAILYMMNNEQFG 189
                      :||           .|.|.:.:..| .|:.:..|.:|.| .|.||        ||
  Rat    57 ----------RLT-----------PHIDNLEVANS-FAVTNAFCSQFSR-GVYAI--------FG 90

  Fly   190 -HSTASAQYFLQLAGYLGIPVISWNADNSGLERRASQSTLQLQLAPSIEHQSAAMLSILERYKWH 253
             :...|........|.|.:..|:.:....|..      ...:|:.|.::   .|:||::|.|:|.
  Rat    91 FYDKKSVNTITSFCGTLHVSFITPSFPTDGTH------PFVIQMRPDLK---GALLSLIEYYQWD 146

  Fly   254 QFSVVTSQIAGHDDFVQAVRERVAEMQEHFKFTILNSIVV-------TRTSDLMEL-VNSEARVM 310
            :|:.:.....|... :|||.:..||  :.::.|.:|...:       |..|...:| :..|.||:
  Rat   147 KFAYLYDSDRGLST-LQAVLDSAAE--KKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVI 208

  Fly   311 L------LYATQTEAITILRAAEEMKLTGENYV-------------------------------- 337
            |      :.....:.|||   .:.:|  |.:|:
  Rat   209 LDCERDKVNDIVDQVITI---GKHVK--GYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDS 268

  Fly   338 ----WVVSQSVIEKKDAHSQFPVGMLGVHFDTSSAALMNEIS-NAIKIYSYGVEAYLTDPANRDR 397
                ::...|.:|:|    ::|    |.|  |::....:.:: :|:::.:   ||:        |
  Rat   269 LVSKFIERWSTLEEK----EYP----GAH--TATIKYTSALTYDAVQVMT---EAF--------R 312

  Fly   398 RLTTQSLSCEDEGRG---------RWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKI 453
            .|..|.:.....|..         .|..|....:.|:.|.:||  ...||:|..:|...:..:.|
  Rat   313 NLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEG--LSGNIKFDQNGKRINYTINI 375

  Fly   454 MNLRPSANNKNLVWEEIGVWKSWETQKLDIRDIAWP-GNSHAPPQGVPEKFHLKITFLEEAPYIN 517
            |.|:.:...|      ||.|.  |..|:.:.....| ||.   ..|:..| .:.:|.:.|:||:.
  Rat   376 MELKTNGPRK------IGYWS--EVDKMVVTLTELPSGND---TSGLENK-TVVVTTILESPYVM 428

  Fly   518 LSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTY 582
            :.                    .:|||        ...||.:    .|:|:||..:.|:..||.|
  Rat   429 MK--------------------KNHEM--------LEGNERY----EGYCVDLAAEIAKHCGFKY 461

  Fly   583 ELVRVEDGKWGT--LENGKWNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVA 645
            :|..|.|||:|.  .:...|||::.:||..|.|:.:..|.|...||.|:|||:|||..||:|::.
  Rat   462 KLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIK 526

  Fly   646 K----RTGIISPTAFLEPFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLY--------LQ 698
            |    :.|:.|   ||:|.....||.: :.|....:.::||....||..:..:.:        .:
  Rat   527 KPQKSKPGVFS---FLDPLAYEIWMCI-VFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE 587

  Fly   699 NTNVTPYRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMIT 763
            :||    .|.:|.:.|.......:....: |||..:.|.:..||..|.::.::.||||||||
  Rat   588 STN----EFGIFNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAF--- 644

  Fly   764 REEFHEFSGLNDSRLVHP------FSHKPSFKFGTIPYSHTDSTIHK----YFNVMHNYMRQYNK 818
                     |...|:|.|      .|.:....:||:....|.....:    .|:.|..|||....
  Rat   645 ---------LTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEP 700

  Fly   819 T----SVADGVAAVLNG-NLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYV 878
            :    :.|:|||.|... ...:::.:.|:.:| :.|.:.|..|.||......|||:|..:.|...
  Rat   701 SVFVRTTAEGVARVRKSKGKYAYLLESTMNEY-IEQRKPCDTMKVGGNLDSKGYGIATPKGSSLG 764

  Fly   879 QMFNKRLLEFRANGDLERLRRYWM--TGTCRPGKQEHK-SSDPLALEQFLSAFLLLMAGILLAAL 940
            ...|..:|:....|.|::|:..|.  .|.|..|..:.| .:..|:|......|.:|:.|:.||.|
  Rat   765 NAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAML 829

  Fly   941 LLLLEHVY 948
            :.|:|..|
  Rat   830 VALIEFCY 837

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.