Protein Alignment Nmdar2 and T25E4.2

DIOPT Version :9

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: NP_001364710.1
• Gene: T25E4.2 / 188897
• WormBaseID: WBGene00020804
• Length: 455
• Species: Caenorhabditis elegans
• Alignment Length: 474
• Identity: 87/474 - (18%)
• Similarity: 158/474 - (33%)
• Gaps: 137/474 - (28%)

  Fly   560 YQCCSGFC-----------IDLLEKFAEELGFTYELVRVEDGKWGTLENGKWNGLIADLV-NRKT 612
            |...|.:|           ::.|....:.:..|..:|:::    ..:|..      .|:| |...
 Worm    19 YVSLSNYCWSFNCPKPGAEVEFLNMTFQLMNSTATIVQID----ADIEQS------IDMVSNGSA 73

  Fly   613 DMVLTSLMINTEREAVVDFSEP--FMETGIAIVVAKRTGIISPTAFLEPFDTASWMLVGIVAIQA 675
            |:.|.|.....:|...|||:.|  |:..|..:.......:......|..:||.: :|:....|..
 Worm    74 DITLVSARQTLDRMKKVDFTTPIGFVYYGYLVREIPELAVADYIMRLFDYDTLA-ILISFGLIIG 137

  Fly   676 ATFMIFLFEWLSPSGYDMKLYLQNTNVTPYRFSLFRTYWLVW------AVLFQAAVHVDSPRGFT 734
            |  :::|:.|:                    |.|.....|.|      .::.|....:.||  ..
 Worm   138 A--LLYLYTWI--------------------FGLRVRSLLDWMFISCSGIIHQFMFRISSP--IC 178

  Fly   735 SRFMTNVWALFAVVFLAIYTANLAAFMITREE----FHEFSGLNDSRLVHPFSHKPSFKFGTIPY 795
            :..:...|.|..:|.:..|.|.|.:|::....    |:...|:.::.     .||.    .|:..
 Worm   179 ALVLIGFWLLCCLVIITYYEAKLKSFLLLSHHRGTIFNTLDGVLEAA-----EHKG----WTLVI 234

  Fly   796 SHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGS 860
            .....|.:.|.|.        ::.:..|.:.:.:|     ||......:.|:.||:......:.|
 Worm   235 QERGYTPYLYCNP--------SQCARLDRLKSRIN-----FIGADDDANLLLGQDKHVGFSALAS 286

  Fly   861 WYAMTGYGLAFSRNSKYVQMFNK----RLLEFRANGDLERLRRYWMT---------GTCRPGKQE 912
            ..|.|.. ..|..:||.:.:.:|    ..|.:..|.:::.||..:..         ||.|   ..
 Worm   287 DLAETDI-TYFDYHSKILFVRDKIMAPEYLAYAVNKNVKGLREKFNRAVAYTKSGYGTVR---SR 347

  Fly   913 HKSSDP--------------LALEQF--LSAFLLLMAGILLAALLLLLEHVYFKYIRKRLAKKDG 961
            :.:|.|              |....|  |..|..:..||  |.::.:||.::.:
 Worm   348 YIASFPSYNSVTSQSQTITVLQTSHFIQLYKFCFIFYGI--AIIVFILEIIFHR----------- 399

  Fly   962 GHCCALISLSMGKSLTFRG 980
                      |.|:.||.|
 Worm   400 ----------MTKNFTFFG 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	70/384 (18%)
		Lig_chan	665..928	CDD:278489	53/301 (18%)
T25E4.2	NP_001364710.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900