DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nmdar2 and glr-8

DIOPT Version :9

Sequence 1:NP_001014714.1 Gene:Nmdar2 / 31107 FlyBaseID:FBgn0053513 Length:1083 Species:Drosophila melanogaster
Sequence 2:NP_001368711.1 Gene:glr-8 / 180924 WormBaseID:WBGene00001619 Length:547 Species:Caenorhabditis elegans


Alignment Length:484 Identity:99/484 - (20%)
Similarity:181/484 - (37%) Gaps:108/484 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   512 EAPYINLSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAE 576
            |.||:|.                     .:...||..|.|..          .|..:::|::..:
 Worm    72 EPPYVNY---------------------VNFSDAAVTDKGYG----------PGVVMEILKEIGK 105

  Fly   577 ELGFTYELVRVEDGKWGTLENGKWNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFM--ETG 639
            .|..|||::......||...||.|.|....||..:.|::....::..:|..:.|.:.||.  .||
 Worm   106 RLNLTYEILPALGSTWGEYLNGSWTGAFGQLVRGEVDLLAGGAIMEYDRSVIADLTYPFQFEPTG 170

  Fly   640 IAIVVAKRTGIISPTAFLEPFDTASWML-VGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVT 703
            |.|...::....:.....|||....|:: ..::.|....|::.       :....|:|.:.| ||
 Worm   171 IMIRSPEKYEDDTLLIVTEPFSWEVWVITAAVILISGVIFLVM-------TNIIRKVYEEMT-VT 227

  Fly   704 PYRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFH 768
            |     |.:.|:.:::..|..: .:.||.::.|.:..:|.|.::...|.:|.:|.|.....:...
 Worm   228 P-----FESIWVFFSIFVQQGL-PEQPRSWSCRVLVALWWLASITLSATFTGSLVALFAVDKTNV 286

  Fly   769 EFSGLND-SRLVHPFSHKPSFKFGTI----PYSHTD----STIHKYFNVMH----NYMRQYNKTS 820
            .|..::. .|||      ...||..:    .::.|:    |.:..|.::.|    |:..:| ...
 Worm   287 PFQNIDQLVRLV------KQGKFEIVMDENSFTRTEMIARSKLPVYRDLWHEMIVNHKVKY-VNG 344

  Fly   821 VADGVA--------AVLN--GNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNS 875
            :|.|||        |:|.  ..|:.:.|            .||:::............:...:||
 Worm   345 IARGVAFVRANPGYALLGPMATLNFYAY------------SDCKVILFNDGILPVYLSIPLVKNS 397

  Fly   876 KYVQMFNKRLLEFRANGDLERLRRYWMT-----------GTCRPGKQEHKSSDPLALEQFLSAFL 929
            .|...|:.::.|....|..::    |:.           ..|.......||.  |.|::...||.
 Worm   398 IYSPYFSTKIREMVERGFTQK----WIADYRSYVAMQKINECNSTTIGPKSY--LDLKRAQGAFW 456

  Fly   930 LLMAGILLAALLLLLEHVYFKYIRKRLAK 958
            :.:.|..|...|.:.|.: ||:.|:::.|
 Worm   457 VFLGGAGLGLALFVGEFI-FKFFREKMTK 484

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nmdar2NP_001014714.1 PBP1_iGluR_NMDA_NR2 99..490 CDD:107373
PBP2_iGluR_NMDA_Nr2 502..908 CDD:270436 85/432 (20%)
Lig_chan 665..928 CDD:278489 55/297 (19%)
glr-8NP_001368711.1 PBP2_iGluR_ligand_binding 62..424 CDD:270219 84/419 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1052
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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