Protein Alignment Nmdar2 and glr-1

DIOPT Version :9

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: NP_498887.2
• Gene: glr-1 / 176204
• WormBaseID: WBGene00001612
• Length: 962
• Species: Caenorhabditis elegans
• Alignment Length: 614
• Identity: 163/614 - (26%)
• Similarity: 274/614 - (44%)
• Gaps: 108/614 - (17%)

  Fly   379 KIYSYGVEAYLTDPANRDRRLTTQSLSCEDEGRGRWDNGEIFFKYLRNVSI---EGDLNKPNIEF 440
            :.::.|......||.: ||....:..|       .:::|:......||:.|   ||.|. .||||
 Worm   345 RFFNRGFPGIYCDPLS-DRSHPNRPFS-------SFEHGKTIGVAFRNMKIGHKEGTLT-GNIEF 400

  Fly   441 TADGDLRSAELKIM----NLRPSANNKN-LVWEE-IGVWKSWETQKLDIRDIAWPG----NSHAP 495
            ...|:.::.::.|:    |.:.:.|:|. |.|.: :|.:.:        |.:|...    |.|..
 Worm   401 DRFGNRKNFDVSIVDLVSNTKATFNSKEVLAWRQGVGFFSN--------RTVAQHSRKSQNDHKD 457

  Fly   496 PQGVPEKFHLKITFLEEAPYINLSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFY 560
            .|.:      .:|.| .||::      .:..:||             |||   ::.:...|..|
 Worm   458 NQVI------VLTNL-VAPFV------MIKRECL-------------EMA---NLTECQGNNKF- 492

  Fly   561 QCCSGFCIDLLEKFAEEL-GFTYELVRVEDGKWGT-----LENGKWNGLIADLVNRKTDMVLTSL 619
               .|||||||:..|::: .|.||:      |.||     ..:|.|:|:|.:|::.:...|:.||
 Worm   493 ---EGFCIDLLKLLADKIEEFNYEI------KLGTKAGSKQADGSWDGMIGELLSGRAHAVVASL 548

  Fly   620 MINTEREAVVDFSEPFMETGIAIVVAK-RTGIISPTAFLEPFDTASWMLVGIVAIQAATFMIFLF 683
            .||.|||.|||||:|||.|||:|::.| .....|..:|::|..|..||.: |.|....:.:|||.
 Worm   549 TINQERERVVDFSKPFMTTGISIMIKKPDKQEFSVFSFMQPLSTEIWMYI-IFAYIGVSVVIFLV 612

  Fly   684 EWLSPSGYDMKLYLQNTNVTPYR----FSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWAL 744
            ...||  |:.:  ::.|:...:.    ||::...|...|...|....: .||..:.|..::.|..
 Worm   613 SRFSP--YEWR--VEETSRGGFTISNDFSVYNCLWFTLAAFMQQGTDI-LPRSISGRIASSAWWF 672

  Fly   745 FAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKFGTIPYSHTDSTIHKYFNV- 808
            |.::.::.||||||||:...:.......:.|      .:.:...|:| |....:.::..||.:|
 Worm   673 FTMIIVSSYTANLAAFLTLEKMQAPIESVED------LAKQSKIKYG-IQGGGSTASFFKYSSVQ 730

  Fly   809 MHNYMRQYNKTSV--------ADGVAAVLN--GNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYA 863
            ::..|.:|.::.|        |:|:..|.:  |.. :|:.:.|..:|...: :.|..|.||:...
 Worm   731 IYQRMWRYMESQVPPVFVASYAEGIERVRSHKGRY-AFLLEATANEYENTR-KPCDTMKVGANLN 793

  Fly   864 MTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYWM--TGTCRPGKQEHKSSDPLALEQFLS 926
            ..|||:|....|.:....|..:|..:..|:|::|...|.  .|.|..|.....||..|.|.:...
 Worm   794 SIGYGIATPFGSDWKDHINLAILALQERGELKKLENKWWYDRGQCDAGITVDGSSASLNLSKVAG 858

  Fly   927 AFLLLMAGILLAALLLLLEHVYFKYIRKR 955
            .|.:||.|::::.|..|.|.:|...|..|
 Worm   859 IFYILMGGMVISMLAALGEFLYRSRIEAR 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373	27/119 (23%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	118/429 (28%)
		Lig_chan	665..928	CDD:278489	68/279 (24%)
glr-1	NP_498887.2	PBP1_iGluR_AMPA	10..439	CDD:107375	25/102 (25%)
		ANF_receptor	44..417	CDD:279440	19/80 (24%)
		Periplasmic_Binding_Protein_Type_2	457..832	CDD:304360	116/428 (27%)
		Lig_chan	593..867	CDD:278489	71/288 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810