Protein Alignment Nmdar2 and glr-3

DIOPT Version :9

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: NP_492017.3
• Gene: glr-3 / 172449
• WormBaseID: WBGene00001614
• Length: 836
• Species: Caenorhabditis elegans
• Alignment Length: 867
• Identity: 196/867 - (22%)
• Similarity: 347/867 - (40%)
• Gaps: 221/867 - (25%)

  Fly   164 LSTLCKEFLRVNVSAILYMMNNEQFGHSTASAQYFLQLAGYLGIPVISWNADNSGLERRASQSTL 228
            |.::| ..|.:..|||:.   .||:....|:|.....:|....:|.:|.:     |......||
 Worm    72 LFSVC-NCLILGASAIIL---PEQYDGHLAAAAIVQSIADNTNVPCVSLH-----LSPPTRPST- 126

  Fly   229 QLQLAPSIEHQSAAMLSILERYKWHQFSVV----------TSQI-AGH---DDF-VQAVR----E 274
              .|.|.:..:|.|:.:.::|.||....||          |..| |||   |.| .|.||    :
 Worm   127 --HLHPHLNAKSLAVAAFIKREKWKDVVVVFEEPDELLEITDMITAGHFDPDSFSSQLVRLKHGD 189

  Fly   275 RVAEMQEHFK-----FTILNSIVVTRTSDLMELVNSEARVMLLY---ATQTEAITI----LRAAE 327
            ......:|.|     :.|:.:|.:.:....:|...:.:...:||   ....:.:|:    :|..|
 Worm   190 DYGNELKHIKNKLDRYRIVINIPLQKALHFLEQAANMSMCGVLYHYVVMDMDLVTVDIDSIRGIE 254

  Fly   328 EMKLT-------GENYVWVVSQSVIEKKDAHSQFPVGMLGVHFDTS----SAALMNEISNAIKIY 381
            :..:|       ...|:..:.|.::.|    |...:...||.:.||    :..|:.....:|:|:
 Worm   255 DCNITSFGVHDVNSEYIEDIRQEIVHK----SSIRLPKKGVPYTTSIWIDTLRLLIRSMKSIQIW 315

  Fly   382 SYGVEAYLTDPANRDRRLTTQSLSCEDEGR--GRWDNG-EIFFKYLRN--VSIEGDLNKPNIEFT 441
                                      ||.|  ..|.:| :|..::..|  ..|.|||:     :.
 Worm   316 --------------------------DEPRCGSSWKSGSDIKKRFFENPLAGISGDLH-----WA 349

  Fly   442 ADGDLRSAELKIMNLRPSANNKNLVWEEIGVWKSWETQKLDIRDIAWPGNSHAPPQGVPEKF--- 503
            ..|:..:..|.:.       .:.|.:::...|.| .|:::...:.....||       .||.
 Worm   350 PSGERSNYTLHVY-------RRTLSFQKFAEWSS-RTRRIASSEAVVIANS-------SEKLTLE 399

  Fly   504 --HLKITFLEEAPYINLSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFYQCCSGF 566
              ||||:...|||::.::                                   .|.|:    .|:
 Worm   400 GKHLKISVYLEAPFVMIT-----------------------------------SNGSY----EGY 425

  Fly   567 CIDLLEKFAEELGFTYELVRVEDGKWGTLE-NGKWNGLIADLVNRKTDMVLTSLMINTEREAVVD 630
            |||||.|.|..|.|||.:.:|.|..:|:.| ||||:|::.:|.....|:.:.||.|:..|..|:|
 Worm   426 CIDLLHKIANILKFTYTIQKVRDNAYGSKESNGKWSGMVGELQRGDADLAVASLTISYGRSEVID 490

  Fly   631 FSEPFMETGIAIVVAK-RTGIISPTAFLEPFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMK 694
            |:.|:|..||:|:..| |........|::|..|..|::.     .|:.|::.:..|:.
 Worm   491 FTVPYMHLGISILFKKPRIRDSDWFKFMDPLSTQVWIMT-----FASYFVVSVAIWII------- 543

  Fly   695 LYLQNTNVTPY-----------------RFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVW 742
                 ..::||                 :|||..::|.....|.|....: .||..::|.:|.:|
 Worm   544 -----AKISPYEQFERDEDNGQYKPVDNQFSLRNSFWFTVCSLMQQGSEL-CPRAASTRLLTGIW 602

  Fly   743 ALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKFGTIPYSHTDSTIHKYFN 807
            ..||::.::.|||||||.:.||.........:|      .:.:...|:||:....|.|    :||
 Worm   603 WFFALILISSYTANLAAVLTTRRMETPIENADD------LAAQTKIKYGTLGRGSTMS----FFN 657

  Fly   808 --VMHNYMRQYNKTSVA---------DGVAAVLNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGSW 861
              .:..|.|.:...|.:         :|:|.|.:.:. :::.:.::|:|.|  :.||.||.:|..
 Worm   658 ESKIETYERMWQLMSSSPGLFVQSSKEGIARVKSSDY-AYLMESSMLEYAV--ERDCELMQIGGL 719

  Fly   862 YAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYW---MTGTCRPGKQEHKSSDPLALEQ 923
            ....|||:...:.|.|.::.:..:|..:...:|..|:..|   .:..|...|::.:...    |.
 Worm   720 IDQKGYGIGLPKGSPYRELISTAILRLQEKTELTELKEKWWKDKSVVCEQPKRKDQDDG----ES 780

  Fly   924 FLSAFLLLMAGILLAALLLLLE 945
            ....|::|:.|::|.|:|::.|
 Worm   781 IGGIFIILVVGLVLTAVLVIFE 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373	74/372 (20%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	110/443 (25%)
		Lig_chan	665..928	CDD:278489	62/293 (21%)
glr-3	NP_492017.3	PBP1_iGluR_non_NMDA-like	21..385	CDD:380591	74/367 (20%)
		Periplasmic_Binding_Protein_Type_2	401..761	CDD:419667	108/429 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810