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Protein Alignment Nmdar2 and Gria1

DIOPT Version :9

Sequence 1:	NP_001014714.1	Gene:	Nmdar2 / 31107	FlyBaseID:	FBgn0053513	Length:	1083	Species:	Drosophila melanogaster
Sequence 2:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus

Alignment Length:	924	Identity:	208/924 - (22%)
Similarity:	355/924 - (38%)	Gaps:	208/924 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 FLKDYSFEQKNIHFDMMSLTPSPTAI--------------LSTLCKEFLRVNVSAILYMMNNEQF 188
            |....|.|.....|.:..||..|..:              ....|.:|.: .|.||        |
Mouse    31 FPNQQSQEHAAFRFALSQLTEPPKLLPQIDIVNISDSFEMTYRFCSQFSK-GVYAI--------F 86

  Fly   189 G-HSTASAQYFLQLAGYLGIPVI--SWNADNSGLERRASQSTLQLQLAPSIEHQSAAMLSILERY 250
            | :...:........|.|.:..|  |:..|.|        :...|||.|.::.   |::||::.|
Mouse    87 GFYERRTVNMLTSFCGALHVCFITPSFPVDTS--------NQFVLQLRPELQE---ALISIIDHY 140

  Fly   251 KWHQFSVVTSQIAGHDDFVQAVRERVAEMQEHFKFTILNSIVVTRTSDLM---ELVNSEARVMLL 312
            ||..|..:.....|. ..:|.|.:..||  ::::.|.:|.:..|.....|   :|...:.|::::
Mouse   141 KWQTFVYIYDADRGL-SVLQRVLDTAAE--KNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVV 202

  Fly   313 YATQTEAITILRAAEEMKLTGENYVWVVSQ------SVIEKKDAHSQFPVGMLGVHFDTSSAALM 371
            .........||....:::..|..|.::::.      .:.:.|::.:......|..:.||..|.:|
Mouse   203 DCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIM 267

  Fly   372 NE--ISNA---------------------IKIYSYGVEAYLTDPANRDRRLTTQSLSCEDEGRG- 412
            .:  .|:|                     :|:.:   ||:        :.|..|.:.....|..
Mouse   268 QQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMA---EAF--------QSLRRQRIDISRRGNAG 321

  Fly   413 --------RWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLVWEE 469
                    .|..|....:.|:.|..||...  |::|...|...:..|.::.::.....|
Mouse   322 DCLANPAVPWGQGIDIQRALQQVRFEGLTG--NVQFNEKGRRTNYTLHVIEMKHDGIRK------ 378

  Fly   470 IGVWKSWETQKLDIRDIAWPGNSHAPPQG----VPEKFHLKITFLEEAPYINLSPADPVSGKCLM 530
            ||.|.  |..|.      .|..:.|...|    |..:.::..|.||: ||:.|..
Mouse   379 IGYWN--EDDKF------VPAATDAQAGGDNSSVQNRTYIVTTILED-PYVMLKK---------- 424

  Fly   531 DRGVLCRVAADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTL 595
                              :..|...|:.:    .|:|::|..:.|:.:|::|.|..|.|||:|..
Mouse   425 ------------------NANQFEGNDRY----EGYCVELAAEIAKHVGYSYRLEIVSDGKYGAR 467

  Fly   596 --ENGKWNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAK----RTGIISPT 654
              :...|||::.:||..:.|:.:..|.|...||.|:|||:|||..||:|::.|    :.|:.|
Mouse   468 DPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFS-- 530

  Fly   655 AFLEPFDTASWMLVGIVAIQAATFMIFL------FEWLS---PSGYDMKLYLQNTNVTPYRFSLF 710
             ||:|.....||.: :.|....:.::||      :||.|   ..|.|     |.|:.....|.:|
Mouse   531 -FLDPLAYEIWMCI-VFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRD-----QTTSDQSNEFGIF 588

  Fly   711 RTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLND 775
            .:.|.......|....: |||..:.|.:..||..|.::.::.||||||||            |..
Mouse   589 NSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAF------------LTV 640

  Fly   776 SRLVHP------FSHKPSFKFGTIPYSHTDSTIHK----YFNVMHNYMRQYNKT----SVADGVA 826
            .|:|.|      .:.:....:||:....|.....:    .|..|..||:....:    :..:|:.
Mouse   641 ERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMI 705

  Fly   827 AVLNG-NLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRA 890
            .|... ...:::.:.|:.:| :.|.:.|..|.||......|||:|..:.|......|..:|:...
Mouse   706 RVRKSKGKYAYLLESTMNEY-IEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSE 769

  Fly   891 NGDLERLRRYWM--TGTCRPGKQEHKSSD---PLALEQFLSAFLLLMAGILLAALLLLLEHVYFK 950
            .|.|::|:..|.  .|.|  |.::..|.|   .|:|......|.:|:.|:.||.|:.|:|   |.
Mouse   770 QGVLDKLKSKWWYDKGEC--GSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIE---FC 829

  Fly   951 YIRKRLAKKDGGHC 964
            |..:..:|:..|.|
Mouse   830 YKSRSESKRMKGFC 843

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.