Protein Alignment Nmdar2 and LOC1276693

DIOPT Version :10

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: XP_061500826.1
• Gene: LOC1276693 / 1276693
• VectorBaseID: AGAMI1_001614
• Length: 972
• Species: Anopheles gambiae
• Alignment Length: 1029
• Identity: 229/1029 - (22%)
• Similarity: 405/1029 - (39%)
• Gaps: 242/1029 - (23%)

  Fly    35 LNTASCQHNSTTSRRKRILTPPSG------PISLLLLTVLTLLILDTRSCQGLRLTNGGGSLSKG 93
            |.|.:..::|:.|.|......|:|      |..:|.|....||:         .|::....:|..
Mosquito     3 LITGTSANSSSRSWRSTNAASPAGVVRRSKPTIMLPLAAALLLV---------ALSHMQTPVSAN 58

  Fly    94 AAANKEQLNIGLIAPHTNFGKREYLRSINNAVTGLTKTRGAKLTFLKDYSFEQKNIHFDMMSLTP 158
            |....|::.:|.|...   |..|...:...|:........|:...|:.|        .|::: |.
Mosquito    59 AQPPTEKIPLGAIFEQ---GTDEIQSAFKFAMLNHNLNVTARRFELQAY--------VDVIN-TA 111

  Fly   159 SPTAILSTLCKEFLRVNVSAILYMMNNEQFG--HSTASAQYFLQLAGYLGIPVIS-WNADNSGLE 220
            ....:...:|.:|.| .|.|:|..::.:.|.  ||.::.         ..:|.:: |..     |
Mosquito   112 DAFKLSKLICNQFSR-GVFAMLGAVSPDSFDTLHSYSNT---------FQMPFVTPWFP-----E 161

  Fly   221 RRASQSTLQLQLAPSIE---HQSAAMLSILERYKW---------HQFSVVTSQI-----AGHDDF 268
            :..:.|:..|..|.|:.   :|  |::..:..|.|         |...:...||     .|::.|
Mosquito   162 KVLTPSSGFLDFAISMRPDYYQ--AIIDTVRYYGWDRIIYMYDSHDGLLRLQQIYQGLRPGNETF 224

  Fly   269 VQAVRERVAEMQEHFKFTILNSIVVTRTSDLMELVN--SEARVMLLYATQTEAITILRAAEEMKL 331
            .....:|:|.:.:..:|        .||   :|.:|  |...::|..:|:.....::....::.|
Mosquito   225 HVETVKRIANVSDAIEF--------LRT---IEELNRWSRKHIVLDCSTELAKDIVVSHVRDITL 278

  Fly   332 TGENYVWVVSQSVIEKKDAHSQFPVGMLGV---------------------HFD-TSSAALMNEI 374
            ....|.:::|..|::.:........|.:.:                     ..| |:|.....|:
Mosquito   279 GKRTYHYLLSGLVMDDRWESEVIEYGAINITGFRIVDTSKKYVKEFLDGWKRLDPTTSQGAGKEL 343

  Fly   375 SNAIKIYSYG-----VEAY----------------------LTDPANRDRRLTTQSLSCEDEGRG 412
            .:|.....|.     |||:                      ...|||     .|::|.| :..:|
Mosquito   344 ISAQAALMYDAVFVLVEAFSKIMRKKPDQFRAYTMRNRGQPFNLPAN-----GTRTLDC-NTSKG 402

  Fly   413 ---RWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLR-PSANNKNLVWEEIG-- 471
               .|::|:...:|||.|.|.|...  :|.|..||..::..|.::.:. .||..|...|.:.|
Mosquito   403 WVTPWEHGDKISRYLRKVEISGLTG--DIRFNEDGKRQNYTLHVVEMTVNSAMVKVAEWSDEGGL 465

  Fly   472 --VWKSWETQKLDIRDIAWPGNSHAPPQGVPEKFHLKITFLEEAPYINLSPADPVSGKCLMDRGV 534
              |...:...|.|:.   :..|          |.::..|.:|| |||.|...:|  |:.|
Mosquito   466 APVVAKYTRLKTDMH---YERN----------KTYIVTTIIEE-PYIMLRQPEP--GETL----- 509

  Fly   535 LCRVAADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLEN-- 597
                               ..||.|    .|:|.||.|..|::||..|||..|:||::|: ||
Mosquito   510 -------------------ETNERF----EGYCKDLAELVAKKLGINYELRIVKDGQYGS-ENPD 550

  Fly   598 --GKWNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISPT--AFLE 658
              |.|:|::.:||.::.|..:..:.|.:|||.|:|||:|||..||:|:: ||.....|:  :||.
Mosquito   551 VKGGWDGMVGELVRKEADFAIAPMTITSERERVIDFSKPFMSLGISIMI-KRPVKQKPSVFSFLN 614

  Fly   659 PFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQN-------TNVTPYRFSLFRTYWLV 716
            |.....|:.| :.:....:.::::....||  ::.:|...|       ...|...||:..::|..
Mosquito   615 PLSKEIWVCV-LFSYVGVSIVLYIVSRFSP--FEWRLVNYNGEQPDAVPQATVNEFSILNSFWFA 676

  Fly   717 WAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHP 781
            .....|....: |||..:.|.:.:||..|.::.::.||||||||            |...|:|.|
Mosquito   677 LGAFMQQGCDI-SPRSISGRIVGSVWWFFTLILISSYTANLAAF------------LTVERMVTP 728

  Fly   782 ------FSHKPSFKFGTIPYSHT-----------DSTIHKYFNV-MHNYMRQYNKTSVADGVAAV 828
                  .:.:...::||:.:..|           .|.:.:|.|. .|.:::.|:     :|:..|
Mosquito   729 INSPEDLASQTEVQYGTLIHGSTWDFFRKSQISLYSRMWEYMNSRKHLFVKSYD-----EGIRRV 788

  Fly   829 LNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGD 893
            ........:...:..:....:.|.|..|.||......|:|:|....|......|..:|..:.||:
Mosquito   789 RTSKGKYALLIESPKNEYTNEREPCDTMKVGRNLDAKGFGIATPLGSPLRDPINLAVLSLKENGE 853

  Fly   894 LERL-RRYWMTGT-CRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLE 945
            |.:| .::|...| |:...::..|.:.|:|......|.:|:.|:|:|..:.|:|
Mosquito   854 LTKLVNKWWFDRTECKHYDKQDASRNELSLSNVAGIFYILIGGLLVALAVALVE 907

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..485	CDD:380601	88/464 (19%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	115/438 (26%)
LOC1276693	XP_061500826.1	None