Protein Alignment Nmdar2 and Nmdar2

DIOPT Version :10

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: XP_061504088.1
• Gene: Nmdar2 / 1275196
• VectorBaseID: AGAMI1_003064
• Length: 910
• Species: Anopheles gambiae
• Alignment Length: 914
• Identity: 772/914 - (84%)
• Similarity: 828/914 - (90%)
• Gaps: 16/914 - (1%)

  Fly   182 MMNNEQFGHSTASAQYFLQLAGYLGIPVISWNADNSGLERRASQSTLQLQLAPSIEHQSAAMLSI 246
            |||.|.:|.||||||||||||||||||||||||||||||||||||.|||||||||||||||||||
Mosquito     1 MMNYESYGRSTASAQYFLQLAGYLGIPVISWNADNSGLERRASQSALQLQLAPSIEHQSAAMLSI 65

  Fly   247 LERYKWHQFSVVTSQIAGHDDFVQAVRERVAEMQEHFKFTILNSIVVTRTSDLMELVNSEARVML 311
            ||||||||||||||||||||||||||||:|..| :||||||||||:|||.|||:|||||||||||
Mosquito    66 LERYKWHQFSVVTSQIAGHDDFVQAVREQVGAM-DHFKFTILNSIIVTRPSDLLELVNSEARVML 129

  Fly   312 LYATQTEAITILRAAEEMKLTGENYVWVVSQSVIEKKDAHSQFPVGMLGVHFDTSSAALMNEISN 376
            ||.|::|||.||.||||:::|||||||||:|||||....|.|||:|||||||||||.||:|||:.
Mosquito   130 LYCTKSEAIEILHAAEELQITGENYVWVVTQSVIENTQTHPQFPIGMLGVHFDTSSGALVNEIAT 194

  Fly   377 AIKIYSYGVEAYLTDPANRDRRLTTQSLSCEDEGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFT 441
            ||::|:||||.||.|..|..|||.|..|||||:||||||:||:|||||||||:|.:.||||||||
Mosquito   195 AIRVYAYGVEYYLNDVKNTGRRLDTHQLSCEDQGRGRWDSGEVFFKYLRNVSLESESNKPNIEFT 259

  Fly   442 ADGDLRSAELKIMNLRPSANNKNLVWEEIGVWKSWETQKLDIRDIAWPGNSHAPPQGVPEKFHLK 506
            |||||:||||||||||||.|:|.|||||||:||||:.|||||||||||||||.||||||||||||
Mosquito   260 ADGDLKSAELKIMNLRPSVNSKGLVWEEIGIWKSWQQQKLDIRDIAWPGNSHTPPQGVPEKFHLK 324

  Fly   507 ITFLEEAPYINLSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFYQCCSGFCIDLL 571
            |||||||||||||||||||||||||||||||||||||| .|||:||||:|.||||||||||||||
Mosquito   325 ITFLEEAPYINLSPADPVSGKCLMDRGVLCRVAADHEM-TDIDMGQAHKNGSFYQCCSGFCIDLL 388

  Fly   572 EKFAEELGFTYELVRVEDGKWGTLENGKWNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFM 636
            |||||||||||||||||||||||||||||||||.:||||||||||||||||.|||||||||||||
Mosquito   389 EKFAEELGFTYELVRVEDGKWGTLENGKWNGLIHELVNRKTDMVLTSLMINAEREAVVDFSEPFM 453

  Fly   637 ETGIAIVVAKRTGIISPTAFLEPFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTN 701
            ||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||..|||..
Mosquito   454 ETGIAIVVAKRTGIISPTAFLEPFDTASWMLVGIFAIQAATFMIFLFEWLSPSGYDMKTVLQNGQ 518

  Fly   702 VTPYRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREE 766
            .|||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||
Mosquito   519 TTPYRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWAMFAVVFLAIYTANLAAFMITREE 583

  Fly   767 FHEFSGLNDSRLVHPFSHKPSFKFGTIPYSHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNG 831
            ||||:||:||||.|||||||:.||||||:|||||||.|||..||.||:|||::||||||.|||:|
Mosquito   584 FHEFTGLDDSRLSHPFSHKPTIKFGTIPWSHTDSTISKYFKEMHYYMKQYNRSSVADGVTAVLSG 648

  Fly   832 NLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLER 896
            .||:||||||||||||.|||||||:|||.||||||||||||||||||.|||||||||||||||||
Mosquito   649 QLDAFIYDGTVLDYLVQQDEDCRLLTVGQWYAMTGYGLAFSRNSKYVGMFNKRLLEFRANGDLER 713

  Fly   897 LRRYWMTGTCRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVYFKYIRKRLAKKDG 961
            |||:||||||||||||||||||||||||||||||||||||||||||||||:||||.||||||||.
Mosquito   714 LRRFWMTGTCRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHLYFKYFRKRLAKKDR 778

  Fly   962 GHCCALISLSMGKSLTFRGAVFEATEILKKHRCNDPICDTHLWKVKHELDMSRLRVRQLEKVMDK 1026
            |.|||||||||||||||||||:||||||::|||||||||||||||||||||||||.:.|||.|..
Mosquito   779 GGCCALISLSMGKSLTFRGAVYEATEILRRHRCNDPICDTHLWKVKHELDMSRLRNQHLEKTMQI 843

  Fly  1027 HGIKAPQLRLASSS------------DLLNHHHLKERPPLLGNLSLAASAQDLYRWSYKTEIAEM 1079
            ||||.||.:|.|::            ||::..:  ::|.|.||||:..|:|||||||||||||||
Mosquito   844 HGIKPPQPKLGSTNKIIRIAGTTGARDLIDDGY--QQPNLFGNLSIGGSSQDLYRWSYKTEIAEM 906

  Fly  1080 ETVL 1083
            ||||
Mosquito   907 ETVL 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..485	CDD:380601	244/302 (81%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	368/405 (91%)
Nmdar2	XP_061504088.1	None