Protein Alignment Nmdar2 and LOC1273165

DIOPT Version :10

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: XP_061503118.1
• Gene: LOC1273165 / 1273165
• VectorBaseID: AGAMI1_009742
• Length: 1024
• Species: Anopheles gambiae
• Alignment Length: 1141
• Identity: 246/1141 - (21%)
• Similarity: 424/1141 - (37%)
• Gaps: 310/1141 - (27%)

  Fly    44 STTSRRKRILTPPSGPISLLLLTVLTLLILDTRSCQGLRLTNG-GGSLSKGAAANKEQLNI-GLI 106
            ::.||||..|.|..  :..||:.....|::..        |:| .|...:..    |.:.| ||.
Mosquito     7 NSESRRKMRLFPMF--LHRLLVVAFAFLLIGP--------TDGYNGDFDEPV----EHIKIGGLF 57

  Fly   107 APHTNFGKREY---LRSINNAVTGLTKTRGAKLTFLKDYSFEQKNI------HFDMMSLTPSPTA 162
            ...|:..:..:   :.::||          .||:: .:|..|.:.:      .||
Mosquito    58 DGDTDDAELAFQYAVEAVNN----------EKLSY-SNYQLEAQAVQVKYGDQFD---------- 101

  Fly   163 ILSTLCKEFLRVNVSAILYMMNNEQFGHST-ASAQYFLQLAGYLGIPVIS--WNADNSGLERRAS 224
            :...||: .|:..|:.|        ||.|: .||.:...:.....:|.|.  |:|       ...
Mosquito   102 VSKKLCR-LLKTGVAGI--------FGPSSPKSALHVQSVCDEKEMPHIETRWDA-------YTK 150

  Fly   225 QSTLQLQLAPSIEHQSAAMLSILERYKWHQFSVVTSQ---IAGHDDFVQAVRERVAEMQEHFKFT 286
            ..||.|...|.|  .....|.::..::|..|:::...   :.|..|.:        :|.:...:|
Mosquito   151 LPTLNLHPHPHI--MGRVFLDLVVAFEWKDFTILYESGPWLPGISDLL--------KMYDPKGYT 205

  Fly   287 IL----------NSIVVTRTSDLMELVNSEARVMLLYATQTEAI-TILRAAEEMKLTGENYVWVV 340
            :.          |...|.|...|.|    :.|::|  |...|:: .:|:.|:::.|..:::
Mosquito   206 VTVRQLDLGLNGNYRAVLRRVKLSE----DKRIIL--ACSIESMPEVLKQAQQVGLLTDHH---- 260

  Fly   341 SQSVIEKKDAHS------QFP-VGMLGVHFDTSSAALMNEISNAIKIYSYGVEAYLTDPAN---- 394
             |.:|...|.|:      |:. ..:.||.........:.::::.:..........|.|..|
Mosquito   261 -QIIITSLDLHTIDLEPYQYSGTNITGVRLIDPEEEKIKQVADFLNASQIAKTLELHDGLNPAKM 324

  Fly   395 -------------------------RDRRLTTQSLSCEDEGRGRWDNGEIFFKYLRNVSIEGDLN 434
                                     ..|.|...||.|:|.  ..|.||.....|:::.:|.| |.
Mosquito   325 RVKTALMYDAVLLFAEALKHLIGSEPPRLLEPISLKCDDP--TTWKNGYSVINYMKSSTIHG-LT 386

  Fly   435 KPNIEFTADGDLRSAELKIMNLRPSANNKNLVWEEIGVWKSWE----TQKLDIRDIAWPGNSHAP 495
            : :|:|...|......|.::.|.|:.      .|::|||.|.|    |:|.:       ..:||.
Mosquito   387 R-SIKFDHQGHRSDFLLDLIELGPAG------LEKVGVWNSTEGLNFTRKTE-------QAAHAM 437

  Fly   496 PQGVPEKFHLKITFLEEAPYINLSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFY 560
            ..|..:    ..|||                       ||..::..:.|..|..: :...||.|
Mosquito   438 DDGTLQ----NRTFL-----------------------VLTAISPPYGMLKDSPI-KLSGNERF- 473

  Fly   561 QCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTL--ENGKWNGLIADLVNRKTDMVLTSLMINT 623
               .||.|||:.:.:..|||.|..:..|||.:|:|  :..||||::.:|:..:.|:.:|.|.|.:
Mosquito   474 ---EGFGIDLIHELSLMLGFNYTFILQEDGVYGSLNRDTKKWNGMVQELLEWRADLAITDLTITS 535

  Fly   624 EREAVVDFSEPFMETGIAIVVAKRTGIISPT-------AFLEPFDTASWMLVGIVAIQAATFMIF 681
            :||:.|||:.|||..||:|:..|      ||       :|:.||....|:.:| .|....:..:|
Mosquito   536 DRESAVDFTMPFMNLGISILFRK------PTKEPPSLFSFMSPFSKQVWLYLG-GAYMMVSMSLF 593

  Fly   682 LFEWLSPSGYDMKLYLQNTNVTPY-----------RFSLFRTYWLVWAVLFQAAVHVDSPRGFTS 735
            :...:||..:|          .||           :||...:.|.....|.|....: :|:...:
Mosquito   594 VLGRISPKEWD----------NPYPCIEEPEELENQFSFSNSMWFTIGALLQQGSEI-APKAPAT 647

  Fly   736 RFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKF--GTIPY--S 796
            |.:.::|..|.::.::.||||||||:...:            :|.|.::......  |.:.|  .
Mosquito   648 RAVASIWWFFTLIMVSSYTANLAAFLTVEQ------------VVSPINNAEDLAAAGGAVKYGAK 700

  Fly   797 HTDSTIHKYFNVMH-NYMRQYN---------KTSVADGVAAVLNGNLDSFIYDGTVLDYLVAQDE 851
            ...|||..:.:..: .|.:.|.         .:|..:|:..|...|. :|:.:.|.::|:|  :.
Mosquito   701 RDGSTISFFKDAEYGTYAKMYQFMMANQDLLTSSNPEGLQRVKTENY-AFLMESTSIEYIV--ER 762

  Fly   852 DCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYWMT-----GTCRPGKQ 911
            :|.:..:|......|||:|..:||.|....::.:|..:..|.|..|:|.|..     |.|....:
Mosquito   763 ECDVTQIGGLLDDKGYGIAMRKNSPYRSALSEAVLRLQEQGVLTSLKRKWWKEKRGGGACENTME 827

  Fly   912 EHKSSDPLALE--QFLSAFLLLMAGILLAALLLLLEHVYFKYIRKRLAK----KDGGH------- 963
            |   ...||||  .....|:||:.|.:.|..:...|.:...:.|.|..|    :||..
Mosquito   828 E---GGALALELANVGGVFVLLIVGCVAALFVSFCEMLCDVHRRTRELKQSTSEDGAEELDMDNV 889

  Fly   964 ------------------CCALISLSMGKS----LTFRGAVFEATEILKKHRCNDPICDTHLWKV 1006
                              ||.|..:...::    :.||..:......:.|       |..:...|
Mosquito   890 GGVFFVLFVGCSFASLFGCCELFFVIAHRARRHKVPFREELMAELRFVAK-------CHGNTKPV 947

  Fly  1007 KHELDMSRLRVRQLEKVMDKHGIKAPQLRLASSSDL 1042
            :|....|......||..|:    .|.|...:|..|:
Mosquito   948 RHRKSSSASGPNSLESGME----SAEQSATSSKQDI 979

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..485	CDD:380601	88/452 (19%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	110/444 (25%)
LOC1273165	XP_061503118.1	None