Protein Alignment Nmdar2 and LOC1272393

DIOPT Version :10

• Sequence 1: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Sequence 2: XP_311343.5
• Gene: LOC1272393 / 1272393
• VectorBaseID: AGAMI1_003669
• Length: 940
• Species: Anopheles gambiae
• Alignment Length: 907
• Identity: 207/907 - (22%)
• Similarity: 360/907 - (39%)
• Gaps: 199/907 - (21%)

  Fly   142 YSFEQKNIHFDMMSLTP-----SPTAILST---LCKEFLRVNVSAILYMMNNEQFGHSTASAQYF 198
            |:.|:.|:|.....|.|     ||.....|   :| |.....|:|:        ||.|:
Mosquito    56 YAVERVNMHEKHFELVPIVRYVSPEDSFRTERKVC-ELAAEGVTAV--------FGPSS------ 105

  Fly   199 LQLAGYLG-------IP--VISWNADN-SGLERRASQSTLQLQLAPSIEHQSAAMLSILERYKWH 253
            |..||.:|       ||  :..|:.:. .|:|  |....:.:.|.|..:..|.|:..::..|.|.
Mosquito   106 LLTAGIVGSICKTLEIPHIITHWDPEPLGGIE--AELRAMTINLYPEADVLSRALADLIVDYSWK 168

  Fly   254 QFSVVTS------------QIAGHDDFVQAVRE---------RVAEMQEHFKFTILNSIVVTRTS 297
            .|:::..            ||.|..|....||:         .:.::|...:..|:..|   |..
Mosquito   169 SFTIIYDSDEGLMRLKDILQIHGPADAPITVRQIDDDPDYRPLLKDIQSSGESHIILEI---RPD 230

  Fly   298 DLMELVNSEARVMLLYATQTEAITILRA----AEEMKLTGEN------------------YVWVV 340
            .::||:.....|.:|...|:..||.|.|    .||::.:..|                  :.|
Mosquito   231 RILELLRQAKEVKMLEEYQSYIITSLDAHTIDFEELRYSRSNITALRLMDTKSFDIKNAVHDW-- 293

  Fly   341 SQSVIEKKDAHSQFPVGMLGVHFDTSSAALMNEISNAIKIYSYGVEAYLTDPANRDRRLTTQSLS 405
                 |:.:|..:.|..:...|..|.| ||.|:   |:|||:..:.     ..:....:|...||
Mosquito   294 -----EQGEARMKRPFRVSPEHVHTES-ALYND---AVKIYATAIR-----ELDATEEITPARLS 344

  Fly   406 CEDEGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLVWEEI 470
            |..:...:|..|.....|:: |..|..:..| |.|...|......|.|:.|     :|:..:::|
Mosquito   345 CGSKNLRQWPFGLRIVNYMK-VKTEHGITGP-IIFDDFGRRAHFHLDIIEL-----SKDEGFKKI 402

  Fly   471 GVWKSWETQKLDIRDIAWPGNSHAPPQGVPEKFHLKITFLEEAPYINLSPADPVSGKCLMDRGVL 535
            ..|....            |.::...||  |.:...:..|:...:|                 |.
Mosquito   403 ATWDPTH------------GVNYTRSQG--EVYSQIVESLQNKTFI-----------------VA 436

  Fly   536 CRVAADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLE--NG 598
            .|:.|...|..:...|:.....:.::   |:.::|::..::.|||.|.:..|.|||:|:..  ..
Mosquito   437 SRIGAPFLMFKEKKDGEFLEGNNRFE---GYSLELIDGISKILGFQYRMELVPDGKYGSYNKVTK 498

  Fly   599 KWNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISPT---AFLEPF 660
            ||:||:..|::||.|:.:..|.|..||...|||:.|||..||:|:.||  .:..|.   :||.|.
Mosquito   499 KWDGLVKYLLDRKADLAVCDLTITYERRTAVDFTMPFMTLGISILYAK--PVQQPKDLFSFLSPL 561

  Fly   661 DTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVTPYR---------FSLFRTYWLV 716
            ....|:.:. .|....:.::|:...::|:.::        |..|.:         :.:....||.
Mosquito   562 SLDVWIYMA-TAYLGVSVLLFVLSRMAPADWE--------NPHPCKQDNDEVENIWDMCNALWLT 617

  Fly   717 WAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRL--V 779
            ...:......: .|:..::|.:..:|..||::.|:.|||||||| :|.|..       |:.:  .
Mosquito   618 MGSIMGQGCDI-LPKAISTRLVAGMWWFFALIMLSSYTANLAAF-LTMERM-------DATIESA 673

  Fly   780 HPFSHKPSFKFG------TIPYSHTD--STIHKYFNVMHNYMRQYNKTSVADGVAAVLNG-NLDS 835
            ...:.:...|:|      |:.:..|.  ||..:.:..|.:........|..:|...|:.| .:.:
Mosquito   674 EDLAKQSKIKYGVVMGGSTMAFFQTSNFSTYQRMWASMESARPSVFTKSNDEGRDRVIKGKRMYA 738

  Fly   836 FIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLR-R 899
            |:.:.|.|:|:.  :..|.|..:|......|||:|...||.|....:..:|:.:..|.|.:|: |
Mosquito   739 FLMESTSLEYIT--ERYCDLTQIGGLLDSKGYGIAMPVNSPYRTAISGAVLKMQEEGKLYQLKTR 801

  Fly   900 YWMT----GTCRP---GKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVYFKYIRK 954
            :|..    |.|..   ..||::    |.:......|::|..|...|.|:.:||.::  .:||
Mosquito   802 WWKEMRGGGQCTEVPNSSQENE----LGIGNVGGVFVVLALGCFCAFLIGILEFLW--NVRK 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..485	CDD:380601	88/403 (22%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	103/435 (24%)
LOC1272393	XP_311343.5	None