DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sta and Rpsa

DIOPT Version :9

Sequence 1:	NP_001284785.1	Gene:	sta / 31106	FlyBaseID:	FBgn0003517	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_058834.1	Gene:	Rpsa / 29236	RGDID:	71026	Length:	295	Species:	Rattus norvegicus

Alignment Length:	282	Identity:	174/282 - (61%)
Similarity:	204/282 - (72%)	Gaps:	20/282 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGGLDILSLKEDDITKMLVATTHLGSENVNFQMEQYVYKRRADGVNILNLGKTWEKLQLAARAI 65
            ||||||:|.:||:|:.|.|.|.||||..|::||||||:|||::||:.|:||.:|||||.||||||
  Rat     1 MSGGLDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAI 65

  Fly    66 VAIDNPSDIFVISSRPIGQRAVLKFAKYTDTTPIAGRFTPGAFTNQIQPAFREPRLLVVTDPNTD 130
            |||:||:|:.|||||..|||||||||..|..||||||||||.||||||.|||||||||||||..|
  Rat    66 VAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRAD 130

  Fly   131 HQPIMEASYVNIPVIAFTNTDSPLRYIDIAIPCNNKSAHSIGLMWWLLAREVLRLRGTISRSVEW 195
            |||:.||||||:|.||..||||||||:|||||||||.|||:|||||:|||||||:||||||...|
  Rat   131 HQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPW 195

  Fly   196 PVVVDLFFYRDPEEAEKEEAAAKE------------LLPPPKIEEAVDHPVEETTNWADEVAAET 248
            .|:.||:|||||||.||||.||.|            ..|.|:...|  .|  |..:|::.|...:
  Rat   196 EVMPDLYFYRDPEEIEKEEQAAAEKAVTKEEFQGEWTAPAPEFTAA--QP--EVADWSEGVQVPS 256

  Fly   249 VG----GVEDWNEDTVKTSWGS 266
            |.    ..|||:.......|.:
  Rat   257 VPIQQFPTEDWSAQPATEDWSA 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sta	NP_001284785.1	PTZ00254	1..247	CDD:240331	169/257 (66%)
Rpsa	NP_058834.1	PTZ00254	1..250	CDD:240331	168/252 (67%)
		Interaction with PPP1R16B. /evidence=ECO:0000255\|HAMAP-Rule:MF_03016	54..113		46/58 (79%)
		Laminin-binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03016	161..180		15/18 (83%)
		Laminin-binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03016	205..229		12/23 (52%)
		[DE]-W-[ST] 1	230..232		0/1 (0%)
		Laminin-binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03016	242..295		9/39 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	266..295		3/13 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351160
Domainoid	1	1.000	139	1.000	Domainoid score	I4681
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68249
Inparanoid	1	1.050	344	1.000	Inparanoid score	I2259
OMA	1	1.010	-	-		QHG53661
OrthoDB	1	1.010	-	-		D1129610at2759
OrthoFinder	1	1.000	-	-		FOG0003206
OrthoInspector	1	1.000	-	-		oto97269
orthoMCL	1	0.900	-	-		OOG6_100806
Panther	1	1.100	-	-	LDO	PTHR11489
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2156
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910