DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rush and zfyve26

DIOPT Version :9

Sequence 1:	NP_001284784.1	Gene:	rush / 31105	FlyBaseID:	FBgn0025381	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	XP_021336194.1	Gene:	zfyve26 / 324565	ZFINID:	ZDB-GENE-030131-3286	Length:	2555	Species:	Danio rerio

Alignment Length:	194	Identity:	59/194 - (30%)
Similarity:	76/194 - (39%)	Gaps:	48/194 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 RKSGKK---------PVEN--HAAVWVPDTDASVCMHCKKTQFTFIQRRHHCRNCGAVVCAGCSA 188
            |.||||         |.|.  ....|:||....:||.|::.:||...||||||.||.:||..||:
Zfish  1797 RPSGKKIRPLATPFTPPEKTPDRKDWIPDHKQHICMVCQRERFTMFNRRHHCRRCGRLVCHSCSS 1861

  Fly   189 KKFLLPQQSTKALRVCDACYERLKHVPSSLGSGEDSAAATGAASGNKLNTTAGDSSNDEDSDEET 253
            ||..: ....:.:||||.||                         |..:|   ||..:.:..|..
Zfish  1862 KKMAV-AGFDEPVRVCDQCY-------------------------NFFHT---DSDEELEQGEVA 1897

  Fly   254 ASPGGESHDEPRFYGDNSVLSAVEDS--STITSPSSATTGSLEAPQVTPSVQSSPAAVATTGSH 315
            .||  .|.||..    |.|||..|.|  ....||:.|....|::........|:...||....|
Zfish  1898 GSP--SSIDEVL----NGVLSLPEVSRKQYRLSPNPAENQQLKSEFYYEQAPSASLCVAILTLH 1955

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rush	NP_001284784.1	PH_Phafin2-like	7..129	CDD:269927
		PH	39..131	CDD:278594
		FYVE_PKHF	148..208	CDD:277257	26/59 (44%)
zfyve26	XP_021336194.1	FYVE_ZFY26	1822..1881	CDD:277263	28/84 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1237900at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920