DRSC/TRiP Functional Genomics Resources

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Protein Alignment rush and Plekhf1

DIOPT Version :9

Sequence 1:NP_001284784.1 Gene:rush / 31105 FlyBaseID:FBgn0025381 Length:316 Species:Drosophila melanogaster
Sequence 2:NP_001013166.1 Gene:Plekhf1 / 308543 RGDID:1310544 Length:279 Species:Rattus norvegicus


Alignment Length:292 Identity:144/292 - (49%)
Similarity:187/292 - (64%) Gaps:33/292 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MVDRLVNSEANTRRIASVENCFGSSGVPLAMQGRVLVGEGVLTKMCRKRPKSRQFFLFNDILVYG 65
            |||.|.|:|.|::|||:||||||:||.|||:.||||:|||||||.|||:.|.|.|||||||||||
  Rat     1 MVDHLANTEINSQRIAAVENCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFNDILVYG 65

  Fly    66 NIVIGKKKYNKQHIMPLEEVSLESIADNQTYRNGWYIRTTTKSFVVFAATSTEKQEWMAHINKCV 130
            :||:.|:||..|||:|||||:||.:.:....:|.|.|:|..|||||.||::||:|||::||.:||
  Rat    66 SIVLSKRKYRSQHIIPLEEVTLEPLPETLQAKNRWMIKTAKKSFVVSAASTTERQEWISHIEECV 130

  Fly   131 EDLLRKSGKKPVENHAAVWVPDTDASVCMHCKKTQFTFIQRRHHCRNCGAVVCAGCSAKKFLLPQ 195
            ...|..:|::|...|||.|:||....:||.|.:|:|:.:.||||||.||.||||.||.::||||:
  Rat   131 RRQLLATGRQPTTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRERFLLPR 195

  Fly   196 QSTKALRVCDACY-------------ERLKHVP---SSLGSGEDSAAATGAASGNKLNTTAGDSS 244
            .|.|.||||..||             ||.:..|   :.|||     ...||:||           
  Rat   196 LSPKPLRVCSLCYRELAAQKRREEAKERFRGSPGQLTHLGS-----TMCGASSG----------- 244

  Fly   245 NDEDSDEETASPG-GESHDEPRFYGDNSVLSA 275
            :|:||||:....| |:...:..||......||
  Rat   245 DDDDSDEDREGSGDGDWPTQVEFYASGVSWSA 276

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rushNP_001284784.1 PH_Phafin2-like 7..129 CDD:269927 77/121 (64%)
PH 39..131 CDD:278594 56/91 (62%)
FYVE_PKHF 148..208 CDD:277257 32/59 (54%)
Plekhf1NP_001013166.1 PH_Phafin2-like 7..129 CDD:269927 77/121 (64%)
PH 39..131 CDD:278594 56/91 (62%)
FYVE_PKHF1 148..211 CDD:277293 34/62 (55%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 219..264 17/60 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 60 1.000 Domainoid score I10327
eggNOG 1 0.900 - - E1_KOG1729
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG52283
OrthoDB 1 1.010 - - D1237900at2759
OrthoFinder 1 1.000 - - FOG0002686
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_105889
Panther 1 1.100 - - O PTHR46280
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
109.790

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