DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rush and aka-1

DIOPT Version :9

Sequence 1:	NP_001284784.1	Gene:	rush / 31105	FlyBaseID:	FBgn0025381	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_495565.2	Gene:	aka-1 / 174216	WormBaseID:	WBGene00000101	Length:	1284	Species:	Caenorhabditis elegans

Alignment Length:	179	Identity:	54/179 - (30%)
Similarity:	83/179 - (46%)	Gaps:	30/179 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 WVPDTDASVCMHCKKTQFTFIQRRHHCRNCGAVVCAG-CSAKKFL--LPQQSTK--ALRVCDACY 208
            |:||::...||.| .|:||.|.||||||.||.|:|.. |:.|.||  |.::..|  |:|||..|.
Worm   538 WIPDSECPNCMLC-NTRFTIITRRHHCRACGRVLCGSCCNEKAFLEYLQEEGKKLQAVRVCKPCS 601

  Fly   209 ERLKHVPSSLGSGEDSAAATGAASGNKLNTTAGDSSNDEDSDEETASPGGESHDEPRFYGDNSVL 273
            ..|..:.:.  ..::.......||.|.|   :||.:........|:.|.|....:|..:.:.
Worm   602 AMLARIETH--EQDEQRRRESIASENGL---SGDETISSIPAASTSIPRGVLKTKPTVHVNE--- 658

  Fly   274 SAVEDSSTITSPSSATTGSLEAPQVTPSVQSS--------PAAVATTGS 314
               ||.::.:|.:.:|:|:     |:.|.:.|        |.|.|..|:
Worm   659 ---EDGASTSSQAHSTSGN-----VSDSSRRSVMFRDGVRPGAPADEGN 699

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rush	NP_001284784.1	PH_Phafin2-like	7..129	CDD:269927
		PH	39..131	CDD:278594
		FYVE_PKHF	148..208	CDD:277257	30/63 (48%)
aka-1	NP_495565.2	PTZ00341	<334..>477	CDD:173534
		FYVE_endofin	532..604	CDD:277268	31/66 (47%)
		DUF3480	905..1257	CDD:371829
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2928
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940