Protein Alignment rush and fgd5a

DIOPT Version :10

• Sequence 1: NP_569923.2
• Gene: rush / 31105
• FlyBaseID: FBgn0025381
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: XP_021335470.1
• Gene: fgd5a / 100151562
• ZFINID: ZDB-GENE-090428-3
• Length: 1473
• Species: Danio rerio
• Alignment Length: 256
• Identity: 71/256 - (27%)
• Similarity: 110/256 - (42%)
• Gaps: 65/256 - (25%)

  Fly     3 DRLVNSEANTRRIASVENCFGSSGV-PLAMQGRVLVGEGVLTKMCRKRPKSRQFFLFNDILVY-- 64
            |.|.:.| |..|:..::  :...|. .|...|||.|.||.|.|:.||..:.|..||.||:::|
Zfish  1103 DNLKHGE-NLLRLVHID--YSVRGKRDLLQPGRVFVKEGTLMKVSRKSRQPRHLFLMNDVMLYTY 1164

  Fly    65 ----GNIVIGKKKYNKQHIMPLEEVSL-ESIADN--QTYRNGWYIRTTTKSFVVFAATSTEKQEW 122
                |       ||..::.:.|..:.: :.|.||  .|.|    |..:..:..:.|::..|:::|
Zfish  1165 PQQDG-------KYRLKNTLTLSGMKVSKPIIDNVLNTLR----IEVSDVTITLSASSLGEREDW 1218

  Fly   123 MAHINKCVEDLLRKSGKKPVENHAA--------------VW----------VPDTDASVCMHCKK 163
            ...:::.:.|            |||              :|          ||.:...:||:| .
Zfish  1219 FHTLSRAIAD------------HAAGLNTFSSSSEAREKLWMSLGEAAPVLVPVSHVMMCMNC-T 1270

  Fly   164 TQFTFIQRRHHCRNCGAVVCAGCSAKKFLLPQQSTKALRVCDACYERLK----HVPSSLGS 220
            :.|:...|||||..||.|||..||..::.|.....:..:|||.||..|:    .||.|.||
Zfish  1271 SDFSLTLRRHHCNACGKVVCRSCSRNRYPLKYLKDRMAKVCDHCYAELRKRGGDVPGSCGS 1331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rush	NP_569923.2	PH_Phafin2-like	7..129	CDD:269927	34/131 (26%)
		FYVE_PKHF	148..208	CDD:277257	23/69 (33%)
fgd5a	XP_021335470.1	PTZ00341	<25..149	CDD:173534
		RhoGEF	919..1102	CDD:459876
		PH1_FGD5	1121..1243	CDD:275435	35/144 (24%)
		FYVE_FGD5	1255..1321	CDD:277281	25/66 (38%)
		PH2_FGD5_FGD6	1377..1467	CDD:270057