Protein Alignment Rab27 and RAB3D

DIOPT Version :10

• Sequence 1: NP_726743.1
• Gene: Rab27 / 31103
• FlyBaseID: FBgn0025382
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_004274.1
• Gene: RAB3D / 9545
• HGNCID: 9779
• Length: 219
• Species: Homo sapiens
• Alignment Length: 174
• Identity: 75/174 - (43%)
• Similarity: 111/174 - (63%)
• Gaps: 9/174 - (5%)

  Fly    19 QFLVLGDSGVGKTCLLYQYTDGRFHTQFISTVGIDFREKRLLYNSRGRRH--RIHLQIWDTAGQE 81
            :.|::|:|.||||..|::|.|..|...|:|||||||:.|.:.      ||  ||.||||||||||
Human    24 KLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVY------RHDKRIKLQIWDTAGQE 82

  Fly    82 RFRSLTTAFYRDAMGFLLIFDLTSEKSFLETANWLSQLRTHAYSEDPDVVLCGNKCDLLQLRVVS 146
            |:|::|||:||.||||||::|:.:::||....:|.:|::|::: ::..|:|.||||||...|||.
Human    83 RYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSW-DNAQVILVGNKCDLEDERVVP 146

  Fly   147 RDQVAALCRRYRLPYIETSACTGANVKEAVELLVGRVMERIENA 190
            .:....|.......:.|.||....|||:..|.||..:.|::..:
Human   147 AEDGRRLADDLGFEFFEASAKENINVKQVFERLVDVICEKMNES 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab27	NP_726743.1	P-loop containing Nucleoside Triphosphate Hydrolases	19..187	CDD:476819	75/169 (44%)
RAB3D	NP_004274.1	Rab3	22..186	CDD:206657	74/168 (44%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P63012	49..58		5/8 (63%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P63012	80..96		10/15 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..219		0/1 (0%)