Protein Alignment Rab27 and Rab27b

DIOPT Version :9

• Sequence 1: NP_726743.1
• Gene: Rab27 / 31103
• FlyBaseID: FBgn0025382
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_445911.1
• Gene: Rab27b / 84590
• RGDID: 620114
• Length: 218
• Species: Rattus norvegicus
• Alignment Length: 176
• Identity: 105/176 - (59%)
• Similarity: 137/176 - (77%)
• Gaps: 6/176 - (3%)

  Fly    19 QFLVLGDSGVGKTCLLYQYTDGRFHTQFISTVGIDFREKRLLYN------SRGRRHRIHLQIWDT 77
            :.|.|||||||||..||:|||.:|:.:||:||||||||||::|:      |.|:..::|||:|||
  Rat    11 KLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYDTQGADGSSGKAFKVHLQLWDT 75

  Fly    78 AGQERFRSLTTAFYRDAMGFLLIFDLTSEKSFLETANWLSQLRTHAYSEDPDVVLCGNKCDLLQL 142
            |||||||||||||:||||||||:|||||::|||...||:|||:.:||.|:||:||.|||.|||..
  Rat    76 AGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLLDQ 140

  Fly   143 RVVSRDQVAALCRRYRLPYIETSACTGANVKEAVELLVGRVMERIE 188
            |.|:..|...|..:|.:||.||||.||.||:::||.|:..:|:|:|
  Rat   141 REVNERQARELAEKYGIPYFETSAATGQNVEKSVETLLDLIMKRME 186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab27	NP_726743.1	P-loop_NTPase	19..187	CDD:304359	103/173 (60%)
		RAB	20..186	CDD:197555	103/171 (60%)
Rab27b	NP_445911.1	Rab27A	6..185	CDD:206700	103/173 (60%)
		Effector region. /evidence=ECO:0000250	38..46		6/7 (86%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	225	1.000	Domainoid score	I2454
eggNOG	1	0.900	-	-		E1_KOG0081
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	232	1.000	Inparanoid score	I3344
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1190514at2759
OrthoFinder	1	1.000	-	-		FOG0004299
OrthoInspector	1	1.000	-	-		otm46169
orthoMCL	1	0.900	-	-		OOG6_105898
Panther	1	1.100	-	-	O	PTHR47977
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3032
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.830