Protein Alignment Rab27 and Rab27a

DIOPT Version :10

• Sequence 1: NP_726743.1
• Gene: Rab27 / 31103
• FlyBaseID: FBgn0025382
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_059013.1
• Gene: Rab27a / 50645
• RGDID: 620918
• Length: 221
• Species: Rattus norvegicus
• Alignment Length: 207
• Identity: 114/207 - (55%)
• Similarity: 147/207 - (71%)
• Gaps: 23/207 - (11%)

  Fly    19 QFLVLGDSGVGKTCLLYQYTDGRFHTQFISTVGIDFREKRLLYNSR------GRRHRIHLQIWDT 77
            :||.|||||||||.:|||||||:|:::||:||||||||||::|.:.      ||..|||||:|||
  Rat    11 KFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRANGPDGTVGRGQRIHLQLWDT 75

  Fly    78 AGQERFRSLTTAFYRDAMGFLLIFDLTSEKSFLETANWLSQLRTHAYSEDPDVVLCGNKCDLLQL 142
            |||||||||||||:||||||||:||||:|:|||...||:|||:.|||.|:||:||||||.||...
  Rat    76 AGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQ 140

  Fly   143 RVVSRDQVAALCRRYRLPYIETSACTGANVKEAVELLVGRVMERIENAACNREFSLLLTQSRCLP 207
            |.|..::...|..:|.:||.||||..|.|:.:|:|:|:..:|:|:|               ||:.
  Rat   141 RAVKEEEARELAEKYGIPYFETSAANGTNISQAIEMLLDLIMKRME---------------RCVD 190

  Fly   208 NIAYGQPEDLVR 219
            ....  ||.:||
  Rat   191 KSWI--PEGVVR 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab27	NP_726743.1	P-loop containing Nucleoside Triphosphate Hydrolases	19..187	CDD:476819	106/173 (61%)
Rab27a	NP_059013.1	Rab27A	6..185	CDD:206700	106/173 (61%)
		Effector region. /evidence=ECO:0000250	38..46		6/7 (86%)