Protein Alignment Rab27 and Rab3a

DIOPT Version :10

• Sequence 1: NP_726743.1
• Gene: Rab27 / 31103
• FlyBaseID: FBgn0025382
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_037150.2
• Gene: Rab3a / 25531
• RGDID: 3528
• Length: 220
• Species: Rattus norvegicus
• Alignment Length: 172
• Identity: 75/172 - (43%)
• Similarity: 114/172 - (66%)
• Gaps: 5/172 - (2%)

  Fly    19 QFLVLGDSGVGKTCLLYQYTDGRFHTQFISTVGIDFREKRLLYNSRGRRHRIHLQIWDTAGQERF 83
            :.|::|:|.||||..|::|.|..|...|:|||||||:.|.:..|.:    ||.|||||||||||:
  Rat    24 KILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDK----RIKLQIWDTAGQERY 84

  Fly    84 RSLTTAFYRDAMGFLLIFDLTSEKSFLETANWLSQLRTHAYSEDPDVVLCGNKCDLLQLRVVSRD 148
            |::|||:||.||||:|::|:|:|:||....:|.:|::|::: ::..|:|.|||||:...||||.:
  Rat    85 RTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSW-DNAQVLLVGNKCDMEDERVVSSE 148

  Fly   149 QVAALCRRYRLPYIETSACTGANVKEAVELLVGRVMERIENA 190
            :...|.......:.|.||....|||:..|.||..:.|::..:
  Rat   149 RGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSES 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab27	NP_726743.1	P-loop containing Nucleoside Triphosphate Hydrolases	19..187	CDD:476819	75/167 (45%)
Rab3a	NP_037150.2	Rab3	22..186	CDD:206657	74/166 (45%)
		Switch 1. /evidence=ECO:0000269|PubMed:10025402, ECO:0007744|PDB:1ZBD	49..58		5/8 (63%)
		Switch 2. /evidence=ECO:0000269|PubMed:10025402, ECO:0007744|PDB:1ZBD	80..96		10/15 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..220