Protein Alignment Rab27 and Rab8b

DIOPT Version :10

• Sequence 1: NP_726743.1
• Gene: Rab27 / 31103
• FlyBaseID: FBgn0025382
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_775589.1
• Gene: Rab8b / 235442
• MGIID: 2442982
• Length: 207
• Species: Mus musculus
• Alignment Length: 196
• Identity: 82/196 - (41%)
• Similarity: 128/196 - (65%)
• Gaps: 20/196 - (10%)

  Fly    19 QFLVLGDSGVGKTCLLYQYTDGRFHTQFISTVGIDFREKRLLYNSRGRRHRIHLQIWDTAGQERF 83
            :.|::|||||||||||:::::..|:|.||||:||||:.:.:..:.:    :|.||||||||||||
Mouse    10 KLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGK----KIKLQIWDTAGQERF 70

  Fly    84 RSLTTAFYRDAMGFLLIFDLTSEKSFLETANWLSQLRTHAYSEDPDVVLCGNKCDLLQLRVVSRD 148
            |::|||:||.|||.:|::|:|:||||....||:..:..|| |.|.:.::.|||||:...|.||::
Mouse    71 RTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHA-SSDVERMILGNKCDMNDKRQVSKE 134

  Fly   149 QVAALCRRYRLPYIETSACTGANVKEAVELLVGRVMERIENAACNREFS----------LLLTQS 203
            :...|...|.:.::||||.:..||:||...|...:|.::     ||:.:          :.:|:|
Mouse   135 RGEKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTKL-----NRKMNDSNSSGAGGPVKITES 194

  Fly   204 R 204
            |
Mouse   195 R 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab27	NP_726743.1	P-loop containing Nucleoside Triphosphate Hydrolases	19..187	CDD:476819	77/167 (46%)
Rab8b	NP_775589.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	77/166 (46%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		8/13 (62%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		13/16 (81%)