Protein Alignment Rab27 and aex-6

DIOPT Version :10

• Sequence 1: NP_726743.1
• Gene: Rab27 / 31103
• FlyBaseID: FBgn0025382
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_493376.1
• Gene: aex-6 / 173223
• WormBaseID: WBGene00000089
• Length: 215
• Species: Caenorhabditis elegans
• Alignment Length: 223
• Identity: 112/223 - (50%)
• Similarity: 142/223 - (63%)
• Gaps: 21/223 - (9%)

  Fly    19 QFLVLGDSGVGKTCLLYQYTDGRFHTQFISTVGIDFREKRLLYNSR-----GRRHRIHLQIWDTA 78
            :||.|||||||||..|::|||..|..||||||||||:||:::|.|.     ||..|:.||:||||
 Worm     9 KFLALGDSGVGKTSFLHRYTDNTFTGQFISTVGIDFKEKKVVYKSSRGGFGGRGQRVLLQLWDTA 73

  Fly    79 GQERFRSLTTAFYRDAMGFLLIFDLTSEKSFLETANWLSQLRTHAYSEDPDVVLCGNKCDLLQLR 143
            ||||||||||||:||||||:||||:|:|:|||...:|||||:.|||.|.||:::||||.||...|
 Worm    74 GQERFRSLTTAFFRDAMGFILIFDITNEQSFLNIRDWLSQLKVHAYCEQPDIIICGNKADLENRR 138

  Fly   144 VVSRDQVAALCRRYRLPYIETSACTGANVKEAVELLVGRVMERIENAACNREFSLLLTQSRCLPN 208
            .||..:...|..:..|||.||||||..||:::|:.|:..||:||:.:.......|    |.|...
 Worm   139 QVSTARAKQLADQLGLPYFETSACTSTNVEKSVDCLLDLVMQRIQQSVETSSLPL----SECRGV 199

  Fly   209 IAYGQPEDLVRLHDRREEPCSRRNCRNC 236
            ...|.|.            .:...|.||
 Worm   200 SLDGDPS------------AASSYCANC 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab27	NP_726743.1	P-loop containing Nucleoside Triphosphate Hydrolases	19..187	CDD:476819	102/172 (59%)
aex-6	NP_493376.1	Rab27A	4..182	CDD:206700	102/172 (59%)