Protein Alignment Rab27 and Rab26

DIOPT Version :10

• Sequence 1: NP_726743.1
• Gene: Rab27 / 31103
• FlyBaseID: FBgn0025382
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: XP_038941050.1
• Gene: Rab26 / 171111
• RGDID: 620890
• Length: 328
• Species: Rattus norvegicus
• Alignment Length: 322
• Identity: 93/322 - (28%)
• Similarity: 122/322 - (37%)
• Gaps: 133/322 - (41%)

  Fly     2 RAAPPEPE-----PLQ-----LAGSGE------QFLVLGDSGVGKTCLLYQYTDGRFHT-QFIST 49
            |.|.|.||     |.|     |.|:|:      :.:::|||||||||||.::.||.|.. .||||
  Rat    33 RTARPGPEAPPNGPPQSGRPSLGGTGDFYDVAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFIST 97

  Fly    50 VGIDFREKRLLYNSRGRRHRIHLQIWDTAGQERFRSLTTAFYRDAMGFLLIFDLTSEKSFLETAN 114
            ||||||.|.|..:..    ::.||||||||||||||:|.|:||||.|.         .|.|..::
  Rat    98 VGIDFRNKVLDVDGM----KVKLQIWDTAGQERFRSVTHAYYRDAHGV---------SSLLSVSS 149

  Fly   115 WLSQLRTHA---YSEDPDVV-------------------------------------------LC 133
            .::.||.|.   ..:.|.:|                                           ||
  Rat   150 TVAALRHHQQRFLRQHPGLVDRNPGICPAGRGAHAVGEQGGNLGQSSPSWPHRACHGLALTKSLC 214

  Fly   134 GNKCDLLQLRVVSRDQVAALCR---------------------------------RYRLPYIETS 165
            ..:.|..|.|||.|:....|.:                                 .|.||::|||
  Rat   215 LGQVDSTQERVVKREDGEKLAKVSQNREGEEGLLEIVTLGPPPYAQHLAGSSYLQEYGLPFMETS 279

  Fly   166 ACTGANVKEAVELLVGRVMERIENAACNREFSLLLTQSRCLPNIAYGQPEDLVRLHD--RRE 225
            |.:|.||..|...:...:.:|...|.....|                      ||||  :||
  Rat   280 AKSGLNVDLAFTAIAKELKQRSTKAPSEPRF----------------------RLHDYVKRE 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab27	NP_726743.1	P-loop containing Nucleoside Triphosphate Hydrolases	19..187	CDD:476819	74/247 (30%)
Rab26	XP_038941050.1	P-loop containing Nucleoside Triphosphate Hydrolases	65..326	CDD:476819	83/290 (29%)