DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14780 and Prss36

DIOPT Version :9

Sequence 1:	NP_569920.2	Gene:	CG14780 / 31102	FlyBaseID:	FBgn0025383	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	XP_017167884.1	Gene:	Prss36 / 77613	MGIID:	1924863	Length:	863	Species:	Mus musculus

Alignment Length:	257	Identity:	90/257 - (35%)
Similarity:	124/257 - (48%)	Gaps:	32/257 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SRIINGSVAKADETRHLVSIRLLRHDNNFGSGHICGGALIAPRKVLTAAHCLYNNQRKRFRRASE 95
            |||:.||.|........||:    |.   |.||||||:||||..||:||||...|  .....|.|
Mouse    46 SRIVGGSDAHPGTWPWQVSL----HQ---GGGHICGGSLIAPSWVLSAAHCFVTN--GTLEPADE 101

  Fly    96 FVVVLGTLNRFEHRNGTIVSQVSSMAYMHTFSPDSMRDDVGILFLRTGLPMSPGGGVHLTVAPIQ 160
            ..|:||..::.....|..:..|:::.....:|...:..|:.:|.|.:...:.|      :|.|:.
Mouse   102 LSVLLGVHSQDGPLEGAHMRSVATILIPDNYSTVELGADLALLRLASPAKLGP------SVRPVC 160

  Fly   161 L--AGQITPPGKLCQVAGWGRTEQS---SLSNILLTANVSTIRHQTCRMIY-RSG-------LLP 212
            |  |..:...|..|...|||..:::   .|..:|....:..:....|:.:| |.|       |||
Mouse   161 LPRASHLFAHGTACWATGWGDVQEAVPLPLPWVLQEVELRLLGEAACQCLYSRPGPFNLTFQLLP 225

  Fly   213 GMMCAGRLQGGTDSCQGDSGGPLVHE--GR--LVGVVSWGYGCAEPGLPGVYVDVEYYRQWI 270
            ||:|||...|..|:||||||||||.|  ||  |.|:.|:|:||.....|||:..|..|..||
Mouse   226 GMLCAGYPAGRRDTCQGDSGGPLVCEDGGRWFLAGITSFGFGCGRRNRPGVFTAVAPYESWI 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	32..270	CDD:214473	87/254 (34%)
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	88/255 (35%)
Prss36	XP_017167884.1	Tryp_SPc	48..290	CDD:238113	88/255 (35%)
		Tryp_SPc	331..532	CDD:389826
		Tryp_SPc	607..789	CDD:389826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100