Protein Alignment CG14780 and PRSS56

DIOPT Version :10

• Sequence 1: NP_569920.2
• Gene: CG14780 / 31102
• FlyBaseID: FBgn0025383
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: XP_047301387.1
• Gene: PRSS56 / 646960
• HGNCID: 39433
• Length: 635
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 96/260 - (36%)
• Similarity: 122/260 - (46%)
• Gaps: 31/260 - (11%)

  Fly    32 RIINGSVAKADETRHLVSIRLLRHDNNFGSGHICGGALIAPRKVLTAAHCLYNNQRKRFRRASEF 96
            ||:.||.|.......||.::|       |...:|||.|:|...|||||||......:..     :
Human   104 RIVGGSAAPPGAWPWLVRLQL-------GGQPLCGGVLVAASWVLTAAHCFVGAPNELL-----W 156

  Fly    97 VVVLGTLNRFEHRNGTIVSQVSSMAYMH-TFSPDSMRDDVGILFLRTGLPMSPGGGVHLTVAPIQ 160
            .|.|...:|.|......|:::    ..| .|.|.:..:|:.::.|.|  |:||||.......|.:
Human   157 TVTLAEGSRGEQAEEVPVNRI----LPHPKFDPRTFHNDLALVQLWT--PVSPGGSARPVCLPQE 215

  Fly   161 LAGQITPPGKLCQVAGWGRT-EQSSLSNILLTANVSTIRHQTCRMIYRSGLLPG-MMCAGRLQGG 223
              .|..|.|..|.:||||.. |....:..:..|.|..:...|||.....||.|. |:|||.|.||
Human   216 --PQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGG 278

  Fly   224 TDSCQGDSGGPLV--HEGR-----LVGVVSWGYGCAEPGLPGVYVDVEYYRQWI-EGRSGAPHSR 280
            .|||||||||||.  ..|.     |.||.|||.||.|||.||||..|..::.|: |..|.|..||
Human   279 VDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSR 343

  Fly   281  280
            Human   344  343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	90/248 (36%)
PRSS56	XP_047301387.1	Tryp_SPc	105..335	CDD:238113	90/249 (36%)
		PksD	<178..600	CDD:442550	70/170 (41%)