Protein Alignment CG14780 and PLG

DIOPT Version :10

• Sequence 1: NP_569920.2
• Gene: CG14780 / 31102
• FlyBaseID: FBgn0025383
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_000292.1
• Gene: PLG / 5340
• HGNCID: 9071
• Length: 810
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 89/258 - (34%)
• Similarity: 122/258 - (47%)
• Gaps: 49/258 - (18%)

  Fly    32 RIINGSVAKADETRHLVSIRLLRHDNNFGSGHICGGALIAPRKVLTAAHCLYNNQRKRFRRASEF 96
            |::.|.||........||:|     ..||. |.|||.||:|..||||||||     ::..|.|.:
Human   580 RVVGGCVAHPHSWPWQVSLR-----TRFGM-HFCGGTLISPEWVLTAAHCL-----EKSPRPSSY 633

  Fly    97 VVVLGTLNRFEHRNGTIVSQVSSMAYMHTFSPDSMRDDVGILFLRTGLPMSPGGGVHLTVAPIQL 161
            .|:||.     |:...:...|..:.....|. :..|.|:.:|.|.               :|..:
Human   634 KVILGA-----HQEVNLEPHVQEIEVSRLFL-EPTRKDIALLKLS---------------SPAVI 677

  Fly   162 AGQITP-----PGKL------CQVAGWGRTEQSSLSNILLTANVSTIRHQTC-RMIYRSGLLPGM 214
            ..::.|     |..:      |.:.|||.|:.:..:.:|..|.:..|.::.| |..:.:|.:...
Human   678 TDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQST 742

  Fly   215 -MCAGRLQGGTDSCQGDSGGPLV----HEGRLVGVVSWGYGCAEPGLPGVYVDVEYYRQWIEG 272
             :|||.|.|||||||||||||||    .:..|.||.|||.|||.|..|||||.|..:..||||
Human   743 ELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEG 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	85/254 (33%)
PLG	NP_000292.1	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..145
		KR	183..263	CDD:214527
		KR	273..354	CDD:214527
		KR	375..456	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	396..416
		KR	479..560	CDD:214527
		Tryp_SPc	581..804	CDD:238113	85/254 (33%)