DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14780 and Prss53

DIOPT Version :9

Sequence 1:	NP_569920.2	Gene:	CG14780 / 31102	FlyBaseID:	FBgn0025383	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	260	Identity:	67/260 - (25%)
Similarity:	106/260 - (40%)	Gaps:	62/260 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 HICGGALIAPRKVLTAAHCLYNNQRKRFRRASEFVVVLGTLNRFEHRNGTIVSQVSSMAYMHTFS 127
            |||.|:|:|...|||||||.   ::......|.:.||||:|.:.....|.....|:::.....::
  Rat    60 HICSGSLVADTWVLTAAHCF---EKMATAELSSWSVVLGSLKQEGLSPGAEEVGVAALQLPKAYN 121

  Fly   128 PDSMRDDVGILFLRTGLPMSPGGGVHLTVAPIQLAGQITPPGKLCQVAGWG------------RT 180
            ..|...|:.:|.|...:       ||.|:...|..... |.|..|...||.            ::
  Rat   122 HYSQGSDLALLQLTHPI-------VHTTLCLPQPTHHF-PFGASCWATGWDQNTSDGKYCPRHKS 178

  Fly   181 EQSSLSNIL------------LTANVS------TIRH--------QTCRMIY---RSGLL----- 211
            .:|...::|            |.:.:|      |:|:        .||..:|   ...||
  Rat   179 RESQTGSVLTVLALCSHCVSELDSTLSPLPVSRTLRNLRLRLISRPTCNCLYNRLHQRLLANPAR 243

  Fly   212 PGMMCAGRLQGGTDSCQGDSGGPLV---HEGR--LVGVVSWGYGCAEPGLPGVYVDVEYYRQWIE 271
            .||:|.|...|....||||||||::   .:|.  .||::|:...||:...|.:..|:..:..|::
  Rat   244 SGMLCGGAQPGVQGPCQGDSGGPVMCREPDGHWVQVGIISFTSNCAQEDTPVLLTDMAAHSSWLQ 308

Fly 272 271
Rat 309 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	32..270	CDD:214473	66/257 (26%)
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	67/258 (26%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	67/260 (26%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100