Protein Alignment CG14780 and KLK12

DIOPT Version :10

• Sequence 1: NP_569920.2
• Gene: CG14780 / 31102
• FlyBaseID: FBgn0025383
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 86/257 - (33%)
• Similarity: 117/257 - (45%)
• Gaps: 43/257 - (16%)

  Fly    16 FLLACAAADLQENQQSRIINGSVAKADETRHLVSIRLLRHDNNF-GSGHICGGALIAPRKVLTAA 79
            |||.|... |.:....:|.||:....:.....|.:        | |:...|||.||..|.|||||
Human     6 FLLLCVLG-LSQAATPKIFNGTECGRNSQPWQVGL--------FEGTSLRCGGVLIDHRWVLTAA 61

  Fly    80 HCLYNNQRKRFRRASEFVVVLGTLNRFEHRNGTI--VSQVSSMAYMHTF-----SPDSMRDDVGI 137
            ||          ..|.:.|.||     ||....:  ..|:....:..|.     :..|...|:.:
Human    62 HC----------SGSRYWVRLG-----EHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRL 111

  Fly   138 LFLRTGLPMSPGGGVHLTVAPIQLAGQITPPGKLCQVAGWGRTE--QSSLSNILLTANVSTIRHQ 200
            |.||  ||:.    |..:|.|:.|.......|..|.|:|||.|.  ::...::|...|:|.:.|.
Human   112 LRLR--LPVR----VTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHA 170

  Fly   201 TCRMIYRSGLLPGMMCAGRLQGGTDSCQGDSGGPLVHEGRLVGVVSWGY--GCAEPGLPGVY 260
            ||..:|...:...|:|||.:. |.|:||||||||||..|.|.|:||||.  .|.:.|:||||
Human   171 TCHGVYPGRITSNMVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVY 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	81/240 (34%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	81/240 (34%)