Protein Alignment CG14780 and KLK2

DIOPT Version :10

• Sequence 1: NP_569920.2
• Gene: CG14780 / 31102
• FlyBaseID: FBgn0025383
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 83/254 - (32%)
• Similarity: 110/254 - (43%)
• Gaps: 33/254 - (12%)

  Fly    30 QSRIINGSVAKADETRHLVSIRLLRHDNNFGSGHICGGALIAPRKVLTAAHCLYNNQRKRFRRAS 94
            ||||:.|...:.......|::      .:.|..| |||.|:.|:.||||||||..|.:
Human    22 QSRIVGGWECEKHSQPWQVAV------YSHGWAH-CGGVLVHPQWVLTAAHCLKKNSQ------- 72

  Fly    95 EFVVVLGTLNRFEHRN-GTIVSQVSSMAY----MHTFSPDSMRDDV----GILFLRTGLPMSPGG 150
               |.||..|.||..: |..|....|..:    |......|:|.|.    .::.||...|..
Human    73 ---VWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK--- 131

  Fly   151 GVHLTVAPIQLAGQITPPGKLCQVAGWGRTEQSSL--SNILLTANVSTIRHQTCRMIYRSGLLPG 213
             :...|..:.|..|....|..|..:|||..|....  ...|...::..:.:..|...|...:...
Human   132 -ITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEF 195

  Fly   214 MMCAGRLQGGTDSCQGDSGGPLVHEGRLVGVVSWG-YGCAEPGLPGVYVDVEYYRQWIE 271
            |:|||...||.|:|.||||||||..|.|.|:.||| ..||.|..|.||..|.:||:||:
Human   196 MLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	79/249 (32%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	80/251 (32%)