Protein Alignment CG14780 and PRSS48

DIOPT Version :10

• Sequence 1: NP_569920.2
• Gene: CG14780 / 31102
• FlyBaseID: FBgn0025383
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_001340540.1
• Gene: PRSS48 / 345062
• HGNCID: 24635
• Length: 346
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 109/320 - (34%)
• Similarity: 151/320 - (47%)
• Gaps: 55/320 - (17%)

  Fly     5 GLHGCSYILFWFLLACAAADLQENQQSRIINGSVAKADETRHLVSIRLLRHDNNFGSGHICGGAL 69
            |..||::.|. .||..:... |....||::.|..|.|......||   |..|:||    ||||:|
Human     2 GPAGCAFTLL-LLLGISVCG-QPVYSSRVVGGQDAAAGRWPWQVS---LHFDHNF----ICGGSL 57

  Fly    70 IAPRKVLTAAHCLYNNQRKRFRRASEFVVVLGTLNRFEHRNGTIVSQVSSMAYMHTFSPDSMRDD 134
            ::.|.:||||||:....     ....:.|.||::...:.|..  |....|...:|....|:.. |
Human    58 VSERLILTAAHCIQPTW-----TTFSYTVWLGSITVGDSRKR--VKYYVSKIVIHPKYQDTTA-D 114

  Fly   135 VGILFLRTGLPMSPGGGVHLTVAPI-------QLAGQITPPGKLCQVAGWGRTEQSS---LSNIL 189
            |.:|.|.:.:..:.      .:.||       |||   .||  .|.|.|||:.::||   ..:.|
Human   115 VALLKLSSQVTFTS------AILPICLPSVTKQLA---IPP--FCWVTGWGKVKESSDRDYHSAL 168

  Fly   190 LTANVSTIRHQTCRMIYRS-GL-LPGM--------MCAGRLQGGTDSCQGDSGGPL-VH-EGRLV 242
            ..|.|..|..|.|..:|.. |: ||.:        :|||..|...|||:||||||| .| :|..:
Human   169 QEAEVPIIDRQACEQLYNPIGIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWI 233

  Fly   243 --GVVSWGYGCAEPGLPGVYVDVEYYRQWIEGR-SGAPHSRLATGLFLLLLLPL-LMRCS 298
              ||||||..|.: .|||||.:|.||::||... |.|.:...:..||.::||.| |:|.|
Human   234 QTGVVSWGLECGK-SLPGVYTNVIYYQKWINATISRANNLDFSDFLFPIVLLSLALLRPS 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	89/261 (34%)
PRSS48	NP_001340540.1	Tryp_SPc	28..265	CDD:238113	90/263 (34%)