DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14780 and Habp2

DIOPT Version :9

Sequence 1:	NP_569920.2	Gene:	CG14780 / 31102	FlyBaseID:	FBgn0025383	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_001001505.2	Gene:	Habp2 / 292126	RGDID:	1302979	Length:	558	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	92/270 - (34%)
Similarity:	127/270 - (47%)	Gaps:	35/270 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ACAAADLQENQQSRIINGSVAKADETRHLVSIRL-LRHDNNFGSGHICGGALIAPRKVLTAAHCL 82
            :|...::.|:...||..|..:.|.:....||::. |....:...||.|||:||.|..|||||||.
  Rat   298 SCGKTEMTEHAVKRIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGSLIHPCWVLTAAHCT 362

  Fly    83 YNNQRKRFRRASEFVVVLG--TLNRFEHRNGTI-VSQVSSMAYMHTFSPDSM-RDDVGILFLRTG 143
             :...|..:      ||||  .|.:.|....|. |.::  :.|......|.: .:|:.:|.|:
  Rat   363 -DMSTKHLK------VVLGDQDLKKTESHEQTFRVEKI--LKYSQYNERDEIPHNDIALLKLK-- 416

  Fly   144 LPMSPGGGVHLT-----VAPIQLAGQITPPGKLCQVAGWGRTEQSSLSNILLTANVSTIRHQTC- 202
                |.|| |..     |..:.|.....|.|..|.::|||.||....|..||.|.|..|.:..|
  Rat   417 ----PVGG-HCALESKYVKTVCLPSDPFPSGTECHISGWGVTETGEGSRQLLDAKVKLIANALCN 476

  Fly   203 -RMIYRSGLLPGMMCAGRLQ-GGTDSCQGDSGGPLVHEG----RLVGVVSWGYGCAEPGLPGVYV 261
             |.:|...:...|:|||.|| .|:|:|||||||||..|.    .:.|:||||..|.:.  ||||.
  Rat   477 SRQLYDHTIDDSMICAGNLQKPGSDTCQGDSGGPLTCEKDGTYYVYGIVSWGQECGKK--PGVYT 539

  Fly   262 DVEYYRQWIE 271
            .|..:..||:
  Rat   540 QVTKFLNWIK 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	32..270	CDD:214473	88/254 (35%)
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	88/254 (35%)
Habp2	NP_001001505.2	EGF_CA	71..107	CDD:238011
		KR	191..275	CDD:238056
		Tryp_SPc	312..551	CDD:238113	89/256 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336782
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840