DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14780 and mst1

DIOPT Version :9

Sequence 1:	NP_569920.2	Gene:	CG14780 / 31102	FlyBaseID:	FBgn0025383	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_694512.1	Gene:	mst1 / 259260	ZFINID:	ZDB-GENE-020806-3	Length:	709	Species:	Danio rerio

Alignment Length:	271	Identity:	61/271 - (22%)
Similarity:	105/271 - (38%)	Gaps:	55/271 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 CAAADLQENQQSRIINGSVAKADETRHLVSIRLLRHDNNFGSGHICGGALIAPRKVLTAAHCLYN 84
            |...:.:...:.||:.|:...:..|   ||:|    |..  ..|.|||:|::...|::...|.
Zfish   469 CGKREDRLRSRLRIVGGTPGNSPWT---VSLR----DRK--GNHFCGGSLVSSEWVISTKQCF-- 522

  Fly    85 NQRKRFRRASEFVVVLGTLNRFEHRNGTIVSQVSSMAYMHTFSPDSMRDDVGILFLRTGLPMSPG 149
              ...:...:.:..::|||.| :.:.|               .||..|..:      |.:...|.
Zfish   523 --SSCYVDLTGYTAMMGTLFR-DPKEG---------------EPDLQRISL------TKIVCGPS 563

  Fly   150 GGVHLTVAPIQLAGQ---------------ITPPGKLCQVAGWGRTEQSSLSNILLTANVSTIRH 199
            .. ||.:..::...|               |.|.|.:|::||||.|:......:|..|.:..:.:
Zfish   564 ES-HLVMLQLETPAQFNERVSQICLPPERYIVPDGTICEIAGWGETKGKGDETVLNVAQMPVLSN 627

  Fly   200 QTCRMIYRSGLLPGMMCAGRLQGGTDSCQGDSGGPLVHEGR----LVGVVSWGYGCAEPGLPGVY 260
            :.|...::..:....||....|.|..:|:.|.||||..:..    |.||:.....|...|.|.::
Zfish   628 KDCNQYFKGRVRENEMCTMAFQAGVGACERDYGGPLACQNSDCWVLEGVIIPMRRCGHAGQPNIF 692

  Fly   261 VDVEYYRQWIE 271
            :.|..|..||:
Zfish   693 IRVSVYVDWIK 703

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	32..270	CDD:214473	58/256 (23%)
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	58/256 (23%)
mst1	NP_694512.1	PAN_AP_HGF	24..105	CDD:238532
		KR	109..187	CDD:238056
		KR	192..271	CDD:214527
		KR	284..365	CDD:214527
		KR	370..451	CDD:238056
		Tryp_SPc	481..702	CDD:214473	58/256 (23%)
		Tryp_SPc	482..705	CDD:238113	59/258 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575879
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930