Protein Alignment CG14780 and F12

DIOPT Version :10

• Sequence 1: NP_569920.2
• Gene: CG14780 / 31102
• FlyBaseID: FBgn0025383
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_000496.2
• Gene: F12 / 2161
• HGNCID: 3530
• Length: 615
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 98/267 - (36%)
• Similarity: 132/267 - (49%)
• Gaps: 49/267 - (18%)

  Fly    28 NQQSRIINGSVAKADETRHLVSIRLLRHDNNFGSGH-ICGGALIAPRKVLTAAHCLYNNQRKRFR 91
            :..:|::.|.||......::.::..         || .|.|:||||..||||||||.:      |
Human   368 SSMTRVVGGLVALRGAHPYIAALYW---------GHSFCAGSLIAPCWVLTAAHCLQD------R 417

  Fly    92 RASE-FVVVLGTLNRFEHRNGTI----VSQVSSMAYMHTFSPDSMRDDVGILFLRTGLP-----M 146
            .|.| ..||||.    |.||.:.    ...|.|......|||.|.:.|:.:|.|:....     :
Human   418 PAPEDLTVVLGQ----ERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALL 478

  Fly   147 SPGGGVHLTVAPIQLAGQITPPGK--LCQVAGWGRTEQSS--LSNILLTANVSTIRHQTCRM--I 205
            ||      .|.|:.|......|.:  ||||||||...:.:  .::.|..|.|..:..:.|..  :
Human   479 SP------YVQPVCLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDV 537

  Fly   206 YRSGLLPGMMCAGRLQGGTDSCQGDSGGPLVHEGR-------LVGVVSWGYGCAEPGLPGVYVDV 263
            :.|.:||||:|||.|:||||:||||||||||.|.:       |.|::|||.||.:...||||.||
Human   538 HGSSILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDV 602

  Fly   264 EYYRQWI 270
            .||..||
Human   603 AYYLAWI 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	97/262 (37%)
F12	NP_000496.2	FN2	41..88	CDD:128373
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:394967
		Kringle	217..295	CDD:395005
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..359
		Tryp_SPc	373..612	CDD:238113	97/262 (37%)