DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14780 and Mst1

DIOPT Version :9

Sequence 1:	NP_569920.2	Gene:	CG14780 / 31102	FlyBaseID:	FBgn0025383	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_032269.3	Gene:	Mst1 / 15235	MGIID:	96080	Length:	716	Species:	Mus musculus

Alignment Length:	261	Identity:	65/261 - (24%)
Similarity:	111/261 - (42%)	Gaps:	47/261 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LQENQQSRIINGSVAKADETRHLVSIRLLRHDNNFGSGHICGGALIAPRKVLTAAHCLYNNQRKR 89
            :.::.:.|::.|....:..|   ||:|     |..|. |.|||:|:..:.||||..|:::....
Mouse   481 VDKSNKLRVVGGHPGNSPWT---VSLR-----NRQGQ-HFCGGSLVKEQWVLTARQCIWSCHEP- 535

  Fly    90 FRRASEFVVVLGTLNRFEHRNGTIVSQV-----------SSMAYMHTFSPDSMRDDVGILFLRTG 143
               .:.:.|.|||:|:........:.:|           |.:..:....|..:...|.::.|
Mouse   536 ---LTGYEVWLGTINQNPQPGEANLQRVPVAKAVCGPAGSQLVLLKLERPVILNHHVALICL--- 594

  Fly   144 LPMSPGGGVHLTVAPIQLAGQITPPGKLCQVAGWGRTEQSSLSNILLTANVSTIRHQTCRMIYRS 208
                         .|.|   .:.|||..|::||||.:..:|.:.:|..|:::.|.:|.|...||.
Mouse   595 -------------PPEQ---YVVPPGTKCEIAGWGESIGTSNNTVLHVASMNVISNQECNTKYRG 643

  Fly   209 GLLPGMMCAGRLQGGTDSCQGDSGGPL---VHE-GRLVGVVSWGYGCAEPGLPGVYVDVEYYRQW 269
            .:....:|...|.....:|:||.||||   .|: ..|.|::.....||.|..|.::..|..:..|
Mouse   644 HIQESEICTQGLVVPVGACEGDYGGPLACYTHDCWVLQGLIIPNRVCARPRWPAIFTRVSVFVDW 708

  Fly   270 I 270
            |
Mouse   709 I 709

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	32..270	CDD:214473	63/252 (25%)
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	64/253 (25%)
Mst1	NP_032269.3	PAN_1	25..96	CDD:278453
		KR	108..188	CDD:214527
		KR	191..269	CDD:214527
		KR	291..372	CDD:214527
		KR	377..459	CDD:214527
		Tryp_SPc	488..709	CDD:214473	63/252 (25%)
		Tryp_SPc	489..712	CDD:238113	64/253 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833179
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930