DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14780 and mst1

DIOPT Version :9

Sequence 1:	NP_569920.2	Gene:	CG14780 / 31102	FlyBaseID:	FBgn0025383	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	XP_004915630.2	Gene:	mst1 / 100494056	XenbaseID:	XB-GENE-487985	Length:	736	Species:	Xenopus tropicalis

Alignment Length:	279	Identity:	73/279 - (26%)
Similarity:	116/279 - (41%)	Gaps:	45/279 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LHGCSYILFWFLLACAAADLQENQQSRIINGSVAKADETRHLVSIRLLRHDNNFGSGHICGGALI 70
            :.|...|:|   .:|...:.:.:|::||:.|....:..|   ||:|     |..|. |.|||:|:
Frog   482 IEGAENIVF---DSCGKRNDRSSQRTRIVGGMPGNSPWT---VSLR-----NRQGE-HFCGGSLV 534

  Fly    71 APRKVLTAAHCLYNNQRKRFRRASEFVVVLGTLNRFEH-------RNGTIVSQVSSMAYMHTFSP 128
            ....|::...|..:....    .|.:..|:|||  |::       |....:|::       ...|
Frog   535 KENWVISTRQCFSSCDAD----LSGYQAVMGTL--FKNPSPDDPDRQSVPISKI-------VCGP 586

  Fly   129 DSMRDDVGILFLRTGLPMSPGGGVHLTVAPIQLAGQITPPGKLCQVAGWGRTEQSSLSNILLTAN 193
                .|..::.|:...|::....|.|...|.:  ..|.|....|::||||.|..:...|:|..|.
Frog   587 ----SDSSLVMLKLERPVTLNSRVALICLPPE--RYIVPEATKCEIAGWGDTGGTGHDNVLKIAI 645

  Fly   194 VSTIRHQTCRMIYRS---GLLPGMMCAGRLQGGTDSCQGDSGGP---LVHE-GRLVGVVSWGYGC 251
            ...|.:..|...|||   .:|...||...:.....:|:||.|||   |.|: ..|.||:....||
Frog   646 FHIISNDECNKNYRSQRNKVLDNEMCTKPVPVDVGACEGDYGGPLACLTHDCWVLEGVIVPARGC 710

  Fly   252 AEPGLPGVYVDVEYYRQWI 270
            .:...|.::..|..|..||
Frog   711 GKKNQPAIFTRVSVYVDWI 729

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	32..270	CDD:214473	66/251 (26%)
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	67/252 (27%)
mst1	XP_004915630.2	PAN_AP_HGF	36..114	CDD:238532
		KR	118..198	CDD:214527
		KR	201..279	CDD:214527
		KR	308..390	CDD:214527
		KR	397..474	CDD:412161
		Tryp_SPc	506..732	CDD:238113	67/252 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000