DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MNX1 and ftz

DIOPT Version :9

Sequence 1:	NP_005506.3	Gene:	MNX1 / 3110	HGNCID:	4979	Length:	401	Species:	Homo sapiens
Sequence 2:	NP_477498.1	Gene:	ftz / 40834	FlyBaseID:	FBgn0001077	Length:	410	Species:	Drosophila melanogaster

Alignment Length:	94	Identity:	38/94 - (40%)
Similarity:	55/94 - (58%)	Gaps:	9/94 - (9%)

- Green bases have known domain annotations that are detailed below.

Human   228 DFN-SQAQSNLLGKC---RRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIW 288
            ||| |..:..|...|   :|.|..:|..|.||||.:|..|:|::|.:|.::|.:|.|:|.|:|||
  Fly   237 DFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIW 301

Human   289 FQNRRMKWKRSKKAKEQAAQEAEKQKGGG 317
            |||||||.|     |::....:.:..|.|
  Fly   302 FQNRRMKSK-----KDRTLDSSPEHCGAG 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MNX1	NP_005506.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	37..78
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	101..120
		Homeobox	244..297	CDD:278475	27/52 (52%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	299..401		3/19 (16%)
ftz	NP_477498.1	FTZ	1..248	CDD:281812	4/10 (40%)
ftz	NP_477498.1	Homeobox	257..310	CDD:278475	27/52 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810