DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14777 and SYM1

DIOPT Version :9

Sequence 1:	NP_001162634.1	Gene:	CG14777 / 31099	FlyBaseID:	FBgn0026872	Length:	196	Species:	Drosophila melanogaster
Sequence 2:	NP_013352.1	Gene:	SYM1 / 850953	SGDID:	S000004241	Length:	197	Species:	Saccharomyces cerevisiae

Alignment Length:	193	Identity:	49/193 - (25%)
Similarity:	93/193 - (48%)	Gaps:	22/193 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLQASLGQWRRGSKLHPMAKGALTYAVMWPAGSLIQQAM--EGRKLREYDWARALRFSLFGALYV 70
            |.:|||       |..|....|:....::..|.:..|.:  ..:..:.||:.|..|..::|:|..
Yeast     6 LYEASL-------KRRPKTTNAIMTGALFGIGDVSAQLLFPTSKVNKGYDYKRTARAVIYGSLIF 63

  Fly    71 APTLYGWVR-LTSAMW----PQTNLRTGIVKAITEQLSYGPFACVSFFMGMSLLELKTFSQAVEE 130
            :.....|.: |.:.::    ||.:....:::...:||::.|.....:|..||::|.::|..|..:
Yeast    64 SFIGDKWYKILNNKIYMRNRPQYHWSNMVLRVAVDQLAFAPLGLPFYFTCMSIMEGRSFDVAKLK 128

  Fly   131 TKEKAAPTYKVGVCIWPILQTINFSLVPEHNRVVFVSICSLMWTIFLAYMKTHHEEQSNSAVL 193
            .||:..||......:||:.|.||||:||..:|::.|::.::.|..:|:|        .||.|:
Yeast   129 IKEQWWPTLLTNWAVWPLFQAINFSVVPLQHRLLAVNVVAIFWNTYLSY--------KNSKVM 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14777	NP_001162634.1	Mpv17_PMP22	118..181	CDD:282035	21/62 (34%)
SYM1	NP_013352.1	Mpv17_PMP22	115..176	CDD:397992	20/60 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I2989
eggNOG	1	0.900	-	-		E1_KOG1944
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	73	1.000	Inparanoid score	I1675
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55228
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46501
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.830