DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14777 and PXMP2

DIOPT Version :9

Sequence 1:	NP_001162634.1	Gene:	CG14777 / 31099	FlyBaseID:	FBgn0026872	Length:	196	Species:	Drosophila melanogaster
Sequence 2:	NP_061133.1	Gene:	PXMP2 / 5827	HGNCID:	9716	Length:	195	Species:	Homo sapiens

Alignment Length:	198	Identity:	50/198 - (25%)
Similarity:	92/198 - (46%)	Gaps:	27/198 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVPAAVKL-LQASLGQWRRGS--------KLHPMAKGALTYAVMWPAGSLIQQAMEGRKLRE--- 53
            |.|||.:| .:|.||...|.:        :|:|:...|.|..::...|:.:.|.:|.::.:|
Human     1 MAPAASRLRAEAGLGALPRRALAQYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKENSR 65

  Fly    54 -YDWARALRFSLFGALYVAPT-------LYGWVRLTSAMWPQTNLRTGIVKAITEQLSYGPFACV 110
             .|....||::::|..:..|.       :..|:.      |:..| .|:.:.:.::|.:.|...:
Human    66 SLDVGGPLRYAVYGFFFTGPLSHFFYFFMEHWIP------PEVPL-AGLRRLLLDRLVFAPAFLM 123

  Fly   111 SFFMGMSLLELKTFSQAVEETKEKAAPTYKVGVCIWPILQTINFSLVPEHNRVVFVSICSLMWTI 175
            .||:.|:.||.|..|....:.:....|..::...:|..||.||.:.||...||:|.::.:|.|..
Human   124 LFFLIMNFLEGKDASAFAAKMRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYA 188

  Fly   176 FLA 178
            :||
Human   189 YLA 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14777	NP_001162634.1	Mpv17_PMP22	118..181	CDD:282035	19/61 (31%)
PXMP2	NP_061133.1	Mpv17_PMP22	131..193	CDD:282035	19/61 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1944
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810