Protein Alignment Ns3 and NOA1

DIOPT Version :9

• Sequence 1: NP_001284779.1
• Gene: Ns3 / 31097
• FlyBaseID: FBgn0266284
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_115689.1
• Gene: NOA1 / 84273
• HGNCID: 28473
• Length: 698
• Species: Homo sapiens
• Alignment Length: 444
• Identity: 85/444 - (19%)
• Similarity: 144/444 - (32%)
• Gaps: 152/444 - (34%)

  Fly     6 KGGAPNLGRQLIKDRFGHTQRRKVDNDTMLHTTEL----------QDGYDWGRLNLSSVTEESSF 60
            :|.||...|..:::..  .:||.....:..|::.|          .:|:..|    ..:.|...|
Human    16 RGSAPTAARHGLREPL--LERRCAAASSFQHSSSLGRELPYDPVDTEGFGEG----GDMQERFLF 74

  Fly    61 QAFLRTAELAGT-EFQAEKLNITFVNPKQRVGLLSKTQEQRMHQKHDEHRDQLKIPRRPKWTKET 124
            ..::...|...| |.|.::|                   |:..::.:..|.|.:..||.:..:..
Human    75 PEYILDPEPQPTREKQLQEL-------------------QQQQEEEERQRQQRREERRQQNLRAR 120

  Fly   125 SAEELVRAENE-------------------------AFLDWRRDLALLQEDEEILMTPYEK--NL 162
            |.|..|....:                         .:|...:.|...:.|..:..|..::  .|
Human   121 SREHPVVGHPDPALPPSGVNCSGCGAELHCQDAGVPGYLPREKFLRTAEADGGLARTVCQRCWLL 185

  Fly   163 EFWRQLWRVVERSDVVVQIVDA--RNP---LLFRSADLERYVKEVEPS-------KMNMILVNKS 215
            ...|:..|:....:..:::|.|  |.|   |:....||......:.|.       |..::|.||.
Human   186 SHHRRALRLQVSREQYLELVSAALRRPGPSLVLYMVDLLDLPDALLPDLPALVGPKQLIVLGNKV 250

  Fly   216 DLLTEEQRRHWAEYFDSEGIRTAFYSATLVEEELKREAEEC----LDSFPEVQQLRRAVEEIKQS 276
            |||.:          |:.|.|         :...:|..|:|    |...|..|..:|.|::
Human   251 DLLPQ----------DAPGYR---------QRLRERLWEDCARAGLLLAPGHQGPQRPVKD---- 292

  Fly   277 LDSVEDALNVIEQKYKTIPETQNDELPRLPGDKNS----PRLLSRL------ELIEFLRNI--YT 329
                               |.|:.|.|..|....:    .||:|..      |||..|:..  |.
Human   293 -------------------EPQDGENPNPPNWSRTVVRDVRLISAKTGYGVEELISALQRSWRYR 338

  Fly   330 GPRHTEQHVTVGMVGYPNVGKSSTINSLM-----------TVKKVSVSATPGKT 372
            |        .|.:||..|.|||:..|:|:           .:.:.::|..||.|
Human   339 G--------DVYLVGATNAGKSTLFNTLLESDYCTAKGSEAIDRATISPWPGTT 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns3	NP_001284779.1	RbgA	161..524	CDD:224083	56/251 (22%)
		HSR1_MMR1	164..395	CDD:206750	55/248 (22%)
		p10	<270..312	CDD:177631	6/45 (13%)
		P-loop_NTPase	313..>357	CDD:304359	17/51 (33%)
NOA1	NP_115689.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..66		4/27 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..134		13/72 (18%)
		RbgA	139..660	CDD:331156	60/296 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	279..306		9/49 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900