DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ns3 and AT1G08410

DIOPT Version :9

Sequence 1:	NP_001284779.1	Gene:	Ns3 / 31097	FlyBaseID:	FBgn0266284	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	NP_172317.1	Gene:	AT1G08410 / 837361	AraportID:	AT1G08410	Length:	589	Species:	Arabidopsis thaliana

Alignment Length:	644	Identity:	230/644 - (35%)
Similarity:	327/644 - (50%)	Gaps:	133/644 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKKNKGGAPNLGRQLIKDRFGHTQRRKVDNDTMLHTTELQDGYDWGRLN-------LSSVTEES 58
            |||..|   .:|||.|:|.                |...:|:..|.|:..       |.||||.|
plant     1 MGKSEK---TSLGRSLVKH----------------HNHMIQESKDKGKYYKNLQKKVLESVTEVS 46

  Fly    59 SFQAFLRTAELAGTEFQAEKLNITFVNPKQRVGL-----------LSKTQEQRMHQKHDE--HRD 110
            ...|.:..||      :||:|..  :|......|           :...:|.|..||.:|  |..
plant    47 DIDAIIEQAE------EAERLYT--INHSSSTPLSINLDTNSSSSVIAAEEWREQQKIEEALHAS 103

  Fly   111 QLKIPRRPKWTKETSAEELVRAENEAFLDWRRDLALLQEDEEILMTPYEKNLEFWRQLWRVVERS 175
            .|::||||.||.|.|.|||...|.:|||:|||.|..|:|:|::::||:||||:.|||||||:|||
plant   104 SLQVPRRPPWTPEMSVEELDANEKQAFLNWRRMLVSLEENEKLVLTPFEKNLDIWRQLWRVLERS 168

  Fly   176 DVVVQIVDARNPLLFRSADLERYVKEVEPSKMNMILVNKSDLLTEEQRRHWAEYFDSEGIRTAFY 240
            |::|.:||||:||.:|..|||.|.:|::..|..|:||||:|||..:.|..|||||....|...|:
plant   169 DLIVMVVDARDPLFYRCPDLEAYAQEIDEHKKIMLLVNKADLLPTDVREKWAEYFRLNNILFVFW 233

  Fly   241 S-----ATLVEEELKREAEECLDSFPEVQQLRRAVEEIKQSLDSVEDALNVIEQKYKTIPETQ-- 298
            |     |||..:.||             :|.|:     ..:|...:|            |:..
plant   234 SAIAATATLEGKVLK-------------EQWRQ-----PDNLQKTDD------------PDIMIY 268

  Fly   299 -NDELPRLPGDKNSPRLLSRLEL----IEFLRN---------IYTGPRHTEQHVTVGMVGYPNVG 349
             .||            |||||:.    |..:||         .:||....:|.| ||.|||||||
plant   269 GRDE------------LLSRLQFEAQEIVKVRNSRAASVSSQSWTGEYQRDQAV-VGFVGYPNVG 320

  Fly   350 KSSTINSLMTVKKVSVSATPGKTKRFQTLFLDKDILLCDCPGLVMPSFVLTKADMLLNGILPIDQ 414
            ||||||:|:..|:..|::||||||.||||.:..:::||||||||.|||..::.:|:.:|:||||:
plant   321 KSSTINALVGQKRTGVTSTPGKTKHFQTLIISDELMLCDCPGLVFPSFSSSRYEMIASGVLPIDR 385

  Fly   415 MRDHVPAVNLLCERIPRHVLEDKYGIVIAKPLEGEDMERPPHSEELLLAYGYNRGFMTSNGQPDQ 479
            |.:|..|:.::.:::||.|:|..|.|.:.||...|...||||:.|||.:|..:||::.|:|.||:
plant   386 MTEHREAIQVVADKVPRRVIESVYNISLPKPKTYERQSRPPHAAELLKSYCASRGYVASSGLPDE 450

  Fly   480 ARSARYVLKDYVNGRLLYAMSPPSVPQTEYHTFPERQRRVIEESQLPGQQQRAMRINKSTSKELD 544
            .::||.:||||:.|:|.:...||.:||.:.....:.|..   |..|.|             .|.|
plant   451 TKAARLILKDYIGGKLPHYAMPPGMPQADEPDIEDTQEL---EDILEG-------------SESD 499

  Fly   545 NQFFSDKPTHAHVKG----RTNFPNVRLANDGSLVAGNDPAAKPWRHVKKERREKLRKK 599
            :....|:..:..|.|    ..:..:..|||  .|.:.....||......|:.::..|||
plant   500 DSAVGDETENEQVPGIDDVLDDLSSFDLAN--GLKSSKKVTAKKQTASHKQHKKPQRKK 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ns3	NP_001284779.1	RbgA	161..524	CDD:224083	153/383 (40%)
		HSR1_MMR1	164..395	CDD:206750	102/251 (41%)
		p10	<270..312	CDD:177631	5/44 (11%)
		P-loop_NTPase	313..>357	CDD:304359	27/56 (48%)
AT1G08410	NP_172317.1	RbgA	133..497	CDD:224083	166/422 (39%)
AT1G08410	NP_172317.1	HSR1_MMR1	157..366	CDD:206750	102/251 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1111
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5917
Inparanoid	1	1.050	352	1.000	Inparanoid score	I608
OMA	1	1.010	-	-		QHG55394
OrthoDB	1	1.010	-	-		D839833at2759
OrthoFinder	1	1.000	-	-		FOG0004203
OrthoInspector	1	1.000	-	-		otm3546
orthoMCL	1	0.900	-	-		OOG6_101986
Panther	1	1.100	-	-	LDO	PTHR45709
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2947
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840