Protein Alignment Ns3 and gnl2

DIOPT Version :9

• Sequence 1: NP_001284779.1
• Gene: Ns3 / 31097
• FlyBaseID: FBgn0266284
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_998389.1
• Gene: gnl2 / 793727
• ZFINID: ZDB-GENE-040426-2317
• Length: 727
• Species: Danio rerio
• Alignment Length: 642
• Identity: 151/642 - (23%)
• Similarity: 253/642 - (39%)
• Gaps: 193/642 - (30%)

  Fly    52 SSVTEESSFQAFLRTAELAGTEFQAEKLNITFVNPKQRVGLLSKTQEQRMHQKHDEHRDQLKI-- 114
            :.|.::||.|.|            .|::|....:|.:.|...||.....:|.:...|..::.|
Zfish    84 TKVIKQSSLQKF------------QEEMNAVKKDPYRVVMRQSKLPMSLLHDRIKAHNSKVHILD 136

  Fly   115 -------------PRRPKWT----KETSAEELVRAENEAFLDWRRDLALLQED--------EEIL 154
                         .:||..:    ||.:.:..|.|::.:.   .:|..|:.||        |||.
Zfish   137 TETFETTFGPKAQRKRPNLSVGELKEFAEQAEVSAQSYSA---EKDRDLVSEDSGVKEEAREEIF 198

  Fly   155 MTPYEKNLEFWRQLWRVVERSDVVVQIVDARNPLLFRSADLERYVKEVEPSKMNMILVNKSDLLT 219
            .....|.:  |.:|::|::.|||::|::|||:|:..||..:|.|:|:.:|.|..:.::||.||:.
Zfish   199 KKGQSKRI--WGELYKVIDSSDVIIQVLDARDPMGTRSQSIETYLKKEKPWKHLIFVLNKCDLIP 261

  Fly   220 EEQRRHWAEYFDSEGIRTAFYSATLVEEELKREAEECLDSFPEVQQLRRAVEEIKQSLDSVEDAL 284
            ....:||......|....||:::             ..:||
Zfish   262 TWVTKHWVAVLSQEYPTLAFHAS-------------LTNSF------------------------ 289

  Fly   285 NVIEQKYKTIPETQNDELPRLPGDKNSPRLLSRLELIEFLRNIYTGPRHTE-QHVTVGMVGYPNV 348
                                   .|.|        ||:.||..  |..|:: :.::||.:|||||
Zfish   290 -----------------------GKGS--------LIQLLRQF--GKLHSDKKQISVGFIGYPNV 321

  Fly   349 GKSSTINSLMTVKKVSVSATPGKTKRFQTLFLDKDILLCDCPGLVMPSFVLTKADMLLNGILPID 413
            ||||.||:|.:.|..:|:...|:||.:|.:.|.:.|.|.||||:|.||.. ::.|::|.|::.::
Zfish   322 GKSSIINTLRSKKVCNVAPLAGETKVWQYITLMRRIFLIDCPGVVYPSDD-SETDIVLKGVVQVE 385

  Fly   414 QMR---DHVPAVNLLCERIPRHVLEDKYGIVIAKPLEGEDMERPPHS--EELLLAYGYNRGFMTS 473
            ::|   ||:.||   .||.....::..|.|             |..|  |:.|....:..|.:..
Zfish   386 KIRNPEDHIGAV---LERAKAEYIQKTYRI-------------PSWSSAEDFLEKLAFRTGKLLK 434

  Fly   474 NGQPDQARSARYVLKDYVNGRLLYAMSPPSVPQTEYH------TFPERQRRVIE-ESQLPGQ--- 528
            .|:||....::.||.|:..||:.:.:.||.|...|.:      ..||.:..:.| |::|..|
Zfish   435 GGEPDLPTVSKMVLNDWQRGRIPFFVKPPGVETDEENKAQAMLEMPEMESEMDELENRLEAQDVE 499

  Fly   529 -----QQRAMRINKSTSKELDNQFFSDKPTHAHVKGRTNF----------PNVRLAN-------- 570
                 |....::.|...:|:...|...|.....:.....|          |::..|:
Zfish   500 EASSSQHEEQKLLKKKKEEVQKLFNDVKQNFGKINVAPEFSEEDLVPVEMPDMMDASGSEDEENE 564

  Fly   571 ---------------------DGSLVAGNDPAA--KPWRHVKKERREKLRKKFSHLD 604
                                 :.|.|:.:.|.|  |..:.|.||..||:.|....||
Zfish   565 EEEEEEDDEEKAEEETGEQQEEESSVSDSTPKAGKKSTQEVNKEMDEKIAKLKHFLD 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns3	NP_001284779.1	RbgA	161..524	CDD:224083	100/375 (27%)
		HSR1_MMR1	164..395	CDD:206750	65/231 (28%)
		p10	<270..312	CDD:177631	1/41 (2%)
		P-loop_NTPase	313..>357	CDD:304359	19/44 (43%)
gnl2	NP_998389.1	NGP1NT	44..174	CDD:285379	20/101 (20%)
		RbgA	198..475	CDD:224083	97/365 (27%)
		NGP_1	209..365	CDD:206751	62/225 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910