Protein Alignment Ns3 and gnl3l

DIOPT Version :10

• Sequence 1: NP_569915.1
• Gene: Ns3 / 31097
• FlyBaseID: FBgn0266284
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_001002875.1
• Gene: gnl3l / 442932
• ZFINID: ZDB-GENE-040723-1
• Length: 565
• Species: Danio rerio
• Alignment Length: 526
• Identity: 146/526 - (27%)
• Similarity: 223/526 - (42%)
• Gaps: 153/526 - (29%)

  Fly     2 GKKNKGGAPNLGRQLIKDRFGHTQRRKVDNDTMLHTTELQDGYDWGRLNLSSVTEESSFQAFLRT 66
            |||.|.|..:.|.:                            .|.|..|:.|..|.|..||.||
Zfish    16 GKKPKDGTQSHGGK----------------------------KDPGVPNVRSFKEHSQRQAELR- 51

  Fly    67 AELAGTEFQAEKLNITFVNPKQRVGLLSKTQEQRMHQKHDEHRDQLKIPRRPKWTKETSAEELVR 131
                                |||:      :||:..|:....::.:|  ||.
Zfish    52 --------------------KQRL------EEQQERQRLSREKEMMK--RRS------------- 75

  Fly   132 AENEAFLD-WRRDLALLQ---EDEEILMTPYEKNLEF---------WRQLWRVVERSDVVVQIVD 183
                  || :::|:.|.|   |..||.|...||::.|         .|:..:|:|.:||:::::|
Zfish    76 ------LDSYQKDIQLRQREFEQREIQMQNLEKHVNFETENSRKAYCREFKKVIEAADVILEVLD 134

  Fly   184 ARNPLLFRSADLERYVKEVEPSKMNMILVNKSDLLTEEQRRHWAEYFDSEGIRTAFYSATLVE-E 247
            ||:||..|...:|:.|.:...:|..::::||.||::::....|.:|..:|....||.|:|..: :
Zfish   135 ARDPLGCRCPQVEQAVVQSGTNKKIVLVLNKIDLVSKDIVEKWIKYLRNEFPTVAFKSSTQQQNK 199

  Fly   248 ELKREAEECLDSFPEVQQLRRAVEEIKQSLDSVEDALNVIEQKYKTIPETQNDELPRLPGDKNSP 312
            .|||      ...|..|    |.:|:.:|...|                 ..|.|.:|.|:
Zfish   200 NLKR------SRVPVTQ----ATQELLESSACV-----------------GADCLMKLLGN---- 233

  Fly   313 RLLSRLELIEFLRNIYTGPRHTEQHVTVGMVGYPNVGKSSTINSLMTVKKVSVSATPGKTKRFQT 377
                      :.||     :..:..:|||:||:|||||||.||||...:..:|.||||.||..|.
Zfish   234 ----------YCRN-----QDIKTAITVGVVGFPNVGKSSLINSLKRARACNVGATPGVTKCLQE 283

  Fly   378 LFLDKDILLCDCPGLVMPSFVLTKADMLLNGILPIDQMRDHVPAVNLLCERIPRHVLEDKYGIVI 442
            :.|||.|.|.||||:||.:.. :.|.|:|...:.|:|:.|.:|||..:..|..:..:.|.|||
Zfish   284 VHLDKHIKLLDCPGIVMATST-SDAAMILRNCVKIEQLVDPLPAVEAILRRCNKMQIIDHYGI-- 345

  Fly   443 AKPLEGEDMERPPHSEELLLAYGYNRGFMTSNGQPDQARSARYVLKDYVNGRLLYAMSPPSVPQT 507
                  .|.:.   :.|.|......:|.:...|.||..::|:.||.|:..||:.|...||
Zfish   346 ------PDFQT---AHEFLALLARRQGKLRKGGLPDSDKAAKSVLMDWTGGRISYFTHPP----- 396

  Fly   508 EYHTFP 513
            |.||.|
Zfish   397 ETHTLP 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns3	NP_569915.1	HSR1_MMR1	164..395	CDD:206750	75/240 (31%)
		RbgA	176..495	CDD:440775	98/319 (31%)
gnl3l	NP_001002875.1	GN3L_Grn1	2..73	CDD:462569	23/113 (20%)
		G_path_suppress	38..>114	CDD:464961	28/123 (23%)
		Nucleostemin_like	127..298	CDD:206753	69/216 (32%)
		P-loop containing Nucleoside Triphosphate Hydrolases	249..357	CDD:476819	49/119 (41%)