Protein Alignment Ns3 and Ns1

DIOPT Version :9

• Sequence 1: NP_001284779.1
• Gene: Ns3 / 31097
• FlyBaseID: FBgn0266284
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_732199.2
• Gene: Ns1 / 42060
• FlyBaseID: FBgn0038473
• Length: 581
• Species: Drosophila melanogaster
• Alignment Length: 608
• Identity: 139/608 - (22%)
• Similarity: 238/608 - (39%)
• Gaps: 160/608 - (26%)

  Fly    73 EFQAEKLNITFVNPKQRV-----------GLLSKTQEQRMHQKHDE--HRDQLKIPRRPK--WTK 122
            |.:|.|.|....:.||::           .:|.:.:|.:..|:.:.  .|:..|..|...  .|.
  Fly    33 ERRAAKKNPKKGSKKQKLIQIPNICPFKDDILKEVEEAKQRQEAERLARREAFKAEREQNKFKTL 97

  Fly   123 ETSAEEL--------VRAENEAFLDWRRDLALLQEDEE----ILMTPYEKNLEFWRQLWRVVERS 175
            |:..|:.        :..||:|           |:.:|    ..:|..:...:::::..:|:|.:
  Fly    98 ESMVEDADMRSTVHGIMHENDA-----------QDQDEKKYKNAVTKEQSLKQYFKEFRKVIENA 151

  Fly   176 DVVVQIVDARNPLLFRSADLERYVKEVEPSKMNMILVNKSDLLTEEQRRHWAEYFDSEGIRTAFY 240
            |||:::||||:||..|..::||.|:....:|..::::||:||:..|...:|.:||...|..|||.
  Fly   152 DVVLEVVDARDPLGTRCNEVERAVRGAPGNKRLVLVLNKADLVPRENLNNWIKYFRRSGPVTAFK 216

  Fly   241 SATLVEEELKREAEECLDSFPEVQQLRRAVEEIKQSLDSVEDALNVIEQKYKTIPETQNDELPRL 305
            ::|  :::..|..             ||.:.|:|     .|.|:
  Fly   217 AST--QDQANRLG-------------RRKLREMK-----TEKAM--------------------- 240

  Fly   306 PGDKNSPRLLSRLELIEFLRNIYTGPRHTEQHVTVGMVGYPNVGKSSTINSLMTVKKVSVSATPG 370
               :.|..:.:.| |:..|.| |...:..:..:.||:||.|||||||.||||...:...|.:|||
  Fly   241 ---QGSVCIGAEL-LMSMLGN-YCRNKGIKTSIRVGVVGIPNVGKSSIINSLTRGRSCMVGSTPG 300

  Fly   371 KTKRFQTLFLDKDILLCDCPGLVMPS------FVLTKADMLLNGILPIDQMRDHVPAVNLLCERI 429
            .||..|.:.||..|.|.||||:|..|      .||..|..       :..::|.......:.:|.
  Fly   301 VTKSMQEVELDSKIKLIDCPGIVFTSGGENSHAVLKNAQR-------VGDVKDPFTIAESVLKRA 358

  Fly   430 PRHVLEDKYGIVIAKPLEGEDMERPPHSEELLLAYGYNRGFMTSNGQPDQARSARYVLKDYVNGR 494
            .:......|           |:......||.........|.....|.||...:||.||.|:..|:
  Fly   359 SKEYFCTMY-----------DITNYDTFEEFFAKKAARMGKFLKKGVPDVVAAARSVLNDWNTGK 412

  Fly   495 LLYAMSPPSVP-----------------QTEYHTFPERQRRVIEES----------------QLP 526
            :.|...||.|.                 :.:...|...:..::|..                ::.
  Fly   413 IKYCTQPPEVQEGQSVHISASIVHSEAREFDVENFESMETEILEHCAVKTDDIMEITSTGPLEIR 477

  Fly   527 GQQQRAMRINKSTSKELDNQFFSDKPTHAHVKGRTN---------FPNVRLANDGSLVAGNDPAA 582
            ..::.|...:|.|:..:.::  .:||    .|||..         .|::.|..:.||..|    .
  Fly   478 QPREEAEPADKITASLVIDE--KEKP----AKGRKRKLDEEKEKVDPSLLLEENQSLNKG----I 532

  Fly   583 KPWRHVKKERREKLRKKFSHLDE 605
            |..:.:||::..:..||.|.:.:
  Fly   533 KQMQKLKKKQNVRNEKKISKITD 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns3	NP_001284779.1	RbgA	161..524	CDD:224083	99/401 (25%)
		HSR1_MMR1	164..395	CDD:206750	73/230 (32%)
		p10	<270..312	CDD:177631	4/41 (10%)
		P-loop_NTPase	313..>357	CDD:304359	18/43 (42%)
Ns1	NP_732199.2	GN3L_Grn1	17..88	CDD:285863	11/54 (20%)
		SurA_N_3	59..>150	CDD:304439	16/101 (16%)
		RbgA	121..443	CDD:224083	99/385 (26%)
		Nucleostemin_like	152..322	CDD:206753	69/215 (32%)
		Ras_like_GTPase	271..>400	CDD:206648	44/146 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435327
Domainoid	1	1.000	42	1.000	Domainoid score	I753
eggNOG	1	0.900	-	-		E1_COG1161
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.740