Protein Alignment Ns3 and Gnl2

DIOPT Version :10

• Sequence 1: NP_569915.1
• Gene: Ns3 / 31097
• FlyBaseID: FBgn0266284
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_001020907.1
• Gene: Gnl2 / 362593
• RGDID: 1305006
• Length: 734
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 146/610 - (23%)
• Similarity: 241/610 - (39%)
• Gaps: 176/610 - (28%)

  Fly    11 NLGRQLIKDRFGHTQRRKVDNDTMLHTT-------ELQDGYDWGRLNLSSVTEESSFQAFLRTAE 68
            |:.||  |:|  ...|.||.......:|       .::....|  ...:.|.:::|.|.|
  Rat    42 NMYRQ--KER--RNSRGKVIKPLQYQSTVAPGTVARVEPNIKW--FGNTRVIKQASLQKF----- 95

  Fly    69 LAGTEFQAEKLNITFVNPKQRVGLLSKTQEQRMHQKHDEHRDQLKI---------------PRRP 118
                   .|:::....:|.:.|...||.....:|.:...|..::.|               .:||
  Rat    96 -------QEEMDKVMKDPYKVVMKQSKLPMSLLHDRVQPHNAKVHILDTESFESTFGPKSQRKRP 153

  Fly   119 KWTKETSAEELVRAE--NEAFLDWRRDLALLQED--------EEILMTPYEKNLEFWRQLWRVVE 173
            ..........|..||  .|:: |..:|..|:.||        |||......|.:  |.:|::|::
  Rat   154 NLFASDMQSLLENAEMSTESY-DQGKDRDLVTEDTGVRNEAQEEIYKKGQSKRI--WGELYKVID 215

  Fly   174 RSDVVVQIVDARNPLLFRSADLERYVKEVEPSKMNMILVNKSDLLTEEQRRHWAEYFDSEGIRTA 238
            .||||||::|||:|:..||:.:|.|:|:.:|.|..:.::||.||:.....:.|......:....|
  Rat   216 SSDVVVQVLDARDPMGTRSSHIEAYLKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSKDYPTLA 280

  Fly   239 FYSATLVEEELKREAEECLDSFPEVQQLRRAVEEIKQSLDSVEDALNVIEQKYKTIPETQNDELP 303
            |::                                  ||.:
  Rat   281 FHA----------------------------------SLTN------------------------ 287

  Fly   304 RLPGDKNSPRLLSRLELIEFLRNIYTGPRHTE-QHVTVGMVGYPNVGKSSTINSLMTVKKVSVSA 367
              |..|.:        .|:.||..  |..||: :.::||.:|||||||||.||:|.:.|..:|:.
  Rat   288 --PFGKGA--------FIQLLRQF--GKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAP 340

  Fly   368 TPGKTKRFQTLFLDKDILLCDCPGLVMPSFVLTKADMLLNGILPIDQMR---DHVPAVNLLCERI 429
            ..|:||.:|.:.|.:.|.|.||||:|.|| ..::.|::|.|::.:::::   ||:.||   .||.
  Rat   341 IAGETKVWQYITLMRRIFLIDCPGVVYPS-EDSETDIVLKGVVQVEKIKAPQDHIGAV---LERA 401

  Fly   430 PRHVLEDKYGIVIAKPLEGEDMERPPHSEELLLAYGYNRGFMTSNGQPDQARSARYVLKDYVNGR 494
            ....:...|.|        |..|   ::|:.|.......|.:...|:||....::.||.|:..||
  Rat   402 KPEYISKTYKI--------ESWE---NAEDFLEKLALRTGKLLKGGEPDLLTVSKMVLNDWQRGR 455

  Fly   495 LLYAMSPPSV------------------------PQTE-YHTFPERQRRVIEESQLPG------- 527
            :.:.:.||:.                        |:.| ..|..||...|||:....|
  Rat   456 IPFFVKPPNAEMPTTPQLPPSSPLEVTTETTQNNPEEETIETEVERSDSVIEKEPEAGCSQDENS 520

  Fly   528 -QQQRAMRINKSTSK-ELDNQFFSD 550
             .||...|:.::..| .:..||.:|
  Rat   521 EMQQILARVRQNFGKINVGPQFSAD 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns3	NP_569915.1	HSR1_MMR1	164..395	CDD:206750	65/231 (28%)
		RbgA	176..495	CDD:440775	86/322 (27%)
Gnl2	NP_001020907.1	NGP1NT	43..174	CDD:462379	27/148 (18%)
		NGP_1	209..365	CDD:206751	62/225 (28%)