Protein Alignment Ns3 and lsg1

DIOPT Version :10

• Sequence 1: NP_569915.1
• Gene: Ns3 / 31097
• FlyBaseID: FBgn0266284
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_997807.1
• Gene: lsg1 / 323464
• ZFINID: ZDB-GENE-030131-2184
• Length: 640
• Species: Danio rerio
• Alignment Length: 654
• Identity: 323/654 - (49%)
• Similarity: 422/654 - (64%)
• Gaps: 65/654 - (9%)

  Fly     1 MG-KKNKGGAPNLGRQLIKDRF--GHTQRRKVDNDTMLHTTELQDGYDWGRLNLSSVTEESSFQA 62
            || ||.:|....|||.|||:|.  |...||   |||.|||:||.||||||||||.||||:||...
Zfish     1 MGKKKTRGEGSGLGRALIKERLNAGRGYRR---NDTWLHTSELNDGYDWGRLNLQSVTEQSSLDD 62

  Fly    63 FLRTAELAGTEFQAEKLNITFVNPKQRVGLLSKTQEQRMHQKHDEHRDQLKIPRRPKWTKETSAE 127
            ||.|||||||||.||||||.||..:.|.||||..:.:|:.:.|:|::..|:|||||.|.:.||.|
Zfish    63 FLATAELAGTEFVAEKLNIKFVPAEARAGLLSSEESRRLKKLHEENKQLLRIPRRPPWDESTSPE 127

  Fly   128 ELVRAENEAFLDWRRDLALLQEDEEILMTPYEKNLEFWRQLWRVVERSDVVVQIVDARNPLLFRS 192
            .|.:.|.::||.||||||.|:|::::::||:|:||:||||||||:|||||||||||||||||||.
Zfish   128 VLQQTEKDSFLTWRRDLARLEEEQKLILTPFERNLDFWRQLWRVIERSDVVVQIVDARNPLLFRC 192

  Fly   193 ADLERYVKEVEPSKMNMILVNKSDLLTEEQRRHWAEYFDSEGIRTAFYSATLVEEELKRE--AEE 255
            .|||:|||||...|:||:|:||:||||.||||.||.||..||||..|:||....:.|:.|  .|:
Zfish   193 PDLEKYVKEVSVHKVNMLLLNKADLLTREQRRAWARYFQKEGIRAVFWSALAEAQRLEAEERGED 257

  Fly   256 CLD------------------------SFPEVQQLRRAVEEIKQSLDSVEDALNVIEQKYKTIPE 296
            .:|                        |.|..::.....:|.::..|   :.:.|.|.:::|..|
Zfish   258 AMDQEDQSDTEEETASKNATDHHEENSSSPNEEKDENEQDEEEEGED---ERICVDESEWQTCSE 319

  Fly   297 TQND-----ELPRLPGDK---NSPRLLSRLELIEFLRNIYTGPRHTEQHVTVGMVGYPNVGKSST 353
            ...|     |.|......   ||.|||.:.||:|..:::::||...:..:|||:|||||||||||
Zfish   320 ESGDEDHAEENPESTATSSFYNSSRLLRKNELLEMFKSVHSGPTCKDGQITVGLVGYPNVGKSST 384

  Fly   354 INSLMTVKKVSVSATPGKTKRFQTLFLDKDILLCDCPGLVMPSFVLTKADMLLNGILPIDQMRDH 418
            ||::...||||||||||.||.|||||::..:.|||||||||||||.|||:|:.:|||||||||||
Zfish   385 INTIFRNKKVSVSATPGHTKHFQTLFVEPGLCLCDCPGLVMPSFVSTKAEMICSGILPIDQMRDH 449

  Fly   419 VPAVNLLCERIPRHVLEDKYGIVIAKPLEGEDMERPPHSEELLLAYGYNRGFMTSNGQPDQARSA 483
            |||::|:|:.|||:|||..|||.|.:|.|.||.:|||..||||:||||.|||||::|||||:|||
Zfish   450 VPAISLVCQNIPRNVLEGTYGINIIRPREDEDPDRPPTYEELLMAYGYMRGFMTAHGQPDQSRSA 514

  Fly   484 RYVLKDYVNGRLLYAMSPPSVPQTEYHTFPERQR---RVIEESQLPGQQQRAMRINKSTSKELDN 545
            ||||||||:|:|||...||.:...::.  |:..:   |:....|:.|...:..:: |.....:|.
Zfish   515 RYVLKDYVSGKLLYCHPPPHINPEDFQ--PQHAKFAMRITGAEQIDGSGGKPSKV-KRIENTVDK 576

  Fly   546 QFFSDKPTHAHVKGRTNFPNVRLA-----NDGSLVAG----NDPAAKPW-RHVKKERREKLRKKF 600
            |||......|..||      |::.     ..|.:.||    ...|.||| :|..:.::||:|:..
Zfish   577 QFFHQANVRALTKG------VQMVMGYKPGSGPVEAGKANTEQQAGKPWKKHGNRNKKEKVRRLN 635

  Fly   601 SHLD 604
            .|||
Zfish   636 KHLD 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns3	NP_569915.1	HSR1_MMR1	164..395	CDD:206750	126/264 (48%)
		RbgA	176..495	CDD:440775	187/352 (53%)
lsg1	NP_997807.1	HSR1_MMR1	164..426	CDD:206750	126/264 (48%)
		RbgA	176..526	CDD:440775	187/352 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	251..341		14/92 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	602..640		14/38 (37%)