Protein Alignment Ns3 and Gnl1

DIOPT Version :10

• Sequence 1: NP_569915.1
• Gene: Ns3 / 31097
• FlyBaseID: FBgn0266284
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_997665.1
• Gene: Gnl1 / 309593
• RGDID: 1303051
• Length: 607
• Species: Rattus norvegicus
• Alignment Length: 633
• Identity: 182/633 - (28%)
• Similarity: 274/633 - (43%)
• Gaps: 105/633 - (16%)

  Fly     3 KKNKGGAPNLGRQLIKDRFGHTQRRKVDNDT------MLHTTELQD---------GYDWGRLNLS 52
            ::.|.|..:..|.....|.|..:||:...||      ..|...|..         |||..|..|.
  Rat    20 RERKRGLQDGLRSSSNSRSGSRERREEQTDTSDGESVTHHIRRLNQQPSQGLGPRGYDPNRYRLH 84

  Fly    53 SVTEESSFQAFLRTAELAGTE----FQAEKLNITFVNPKQRVGLLSKTQEQRMHQKHDEHRDQLK 113
              .|..|.:...|....|..:    ..||.|.:..               |.::|.    ...|.
  Rat    85 --FERDSREEVERRKRAAREQVLQPVSAEMLELDI---------------QEVYQP----GSVLD 128

  Fly   114 IPRRPKWTKETSAEELVRAENEAFLDWRRDLALLQEDEEILMTPYEKNLEFWRQLWRVVERSDVV 178
            .||||.|:.|.|.|:|:..|..:|.::...:......|:  ::.:|.|||.|||||||:|.||:|
  Rat   129 FPRRPPWSYEMSKEQLMSQEERSFQEYLGKIHGAYTSEK--LSYFEHNLETWRQLWRVLEMSDIV 191

  Fly   179 VQIVDARNPLLFRSADLERYVKEVEPSKMNMILV---NKSDLLTEEQRRHWAEYFDSE------G 234
            :.|.|.|:|::.....|..||    ..::.:.||   ||.||........|..||...      .
  Rat   192 LLITDIRHPVVNFPPALYEYV----TGELGLALVLVLNKVDLAPPALVVAWKHYFHQHYPQLHIV 252

  Fly   235 IRTAFYSATLVEEE----LKREAE------ECLDSFPEVQQLRRAVEEI---KQSLDSVED--AL 284
            :.|:|...|...:|    ||:...      ..|.  ||  ||.||.|.|   |..|.|..:  |.
  Rat   253 LFTSFPRDTRTPQEPGSVLKKSRRRGRGWTRALG--PE--QLLRACEAITVGKVDLSSWREKIAR 313

  Fly   285 NVIEQKYKTIPETQNDELPRLPGDKNSPRLLSRLELIEFLRNIYTGP---RHTEQHVTVGMVGYP 346
            :|....:..:...:.:|       ::.|.:|...:....:..  |||   |:.:..||:|.||:|
  Rat   314 DVAGASWGNVSGEEEEE-------EDGPAVLVEQQTDSAMEP--TGPSRERYKDGVVTIGCVGFP 369

  Fly   347 NVGKSSTINSLMTVKKVSVSATPGKTKRFQTLFLDKDILLCDCPGLVMPSFVLTKADMLLNGILP 411
            ||||||.||.|:..|.||||.|||.|:.|||.||...:.|||||||:.|| :|.:...:|.||.|
  Rat   370 NVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLCDCPGLIFPS-LLPRQLQVLAGIYP 433

  Fly   412 IDQMRDHVPAVNLLCERIPRHVLEDKYGIVIAKPLEGED--MERPPHSEELLLAYGYNRGFMTSN 474
            |.|:::...:|..|..|||...|     :.:..| |.||  .|.|..:.::..|:...||:.|:.
  Rat   434 IAQIQEPYTSVGYLACRIPVQAL-----LHLRHP-EAEDPSAEHPWCAWDVCEAWAEKRGYKTAK 492

  Fly   475 -GQPDQARSARYVLKDYVNGRLLYAMSPP--SVPQTEYHTFPERQRRVIEESQL--PGQQQRAMR 534
             .:.|..|:|..:|:..|:|||.....||  |..:..:.:..|....|:.:.::  .|.::....
  Rat   493 AARNDVYRAANSLLRLAVDGRLSLCFHPPGYSEQRGTWESHAETAELVLSQGRVGPAGDEEEEEE 557

  Fly   535 INKSTSKELDNQFFSDKPTHAHVKGRTNFPNVRLANDGSLVAGNDPAA 582
            ...|:|.|.:.:  .|:......:|..:.|.   ::.||.:|..:|.|
  Rat   558 EELSSSCEEEGE--EDRDADEEGEGDEDTPT---SDTGSCLAARNPYA 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns3	NP_569915.1	HSR1_MMR1	164..395	CDD:206750	90/257 (35%)
		RbgA	176..495	CDD:440775	112/348 (32%)
Gnl1	NP_997665.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..81		14/60 (23%)
		RbgA	173..514	CDD:440775	124/364 (34%)
		HSR1_MMR1	177..418	CDD:206750	90/257 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	544..607		12/62 (19%)