Protein Alignment Ns3 and Gnl2

DIOPT Version :9

• Sequence 1: NP_001284779.1
• Gene: Ns3 / 31097
• FlyBaseID: FBgn0266284
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_663527.2
• Gene: Gnl2 / 230737
• MGIID: 2385207
• Length: 728
• Species: Mus musculus
• Alignment Length: 617
• Identity: 145/617 - (23%)
• Similarity: 244/617 - (39%)
• Gaps: 160/617 - (25%)

  Fly    11 NLGRQLIKDRFGHTQRRKVDNDTMLHTT-------ELQDGYDWGRLNLSSVTEESSFQAFLRTAE 68
            |:.||  |:|  ...|.||.......:|       .::....|  ...:.|.:::|.|.|
Mouse    42 NMYRQ--KER--RNSRGKVIKPLQYQSTVASGTVARVEPNIKW--FGNTRVIKQASLQKF----- 95

  Fly    69 LAGTEFQAEKLNITFVNPKQRVGLLSKTQEQRMHQKHDEHRDQLKI---------------PRRP 118
                   .|:::....:|.:.|...||.....:|.:...|..::.|               .:||
Mouse    96 -------QEEMDKVMKDPYKVVMKQSKLPMSLLHDRIQPHNAKVHILDTESFESTFGPKSQRKRP 153

  Fly   119 KWTKETSAEELVRAE--NEAFLDWRRDLALLQED--------EEILMTPYEKNLEFWRQLWRVVE 173
            ..........|..||  .|:: |..:|..|:.||        |||......|.:  |.:|::|::
Mouse   154 NLFASDMQSLLENAEMSTESY-DQGKDRDLVMEDTGVRNEAQEEIYKKGQSKRI--WGELYKVID 215

  Fly   174 RSDVVVQIVDARNPLLFRSADLERYVKEVEPSKMNMILVNKSDLLTEEQRRHWAEYFDSEGIRTA 238
            .||||||::|||:|:..||..:|.|:|:.:|.|..:.::||.||:.....:.|
Mouse   216 SSDVVVQVLDARDPMGTRSPHIEAYLKKEKPWKHLIFVLNKCDLVPTWATKRW------------ 268

  Fly   239 FYSATLVEEELKREAEECLDSFPEVQQLRRAVEEIKQSLDSVEDALNVIEQKYKTIPETQNDELP 303
                                                         :.|:.|.|.|:
Mouse   269 ---------------------------------------------VAVLSQDYPTL--------- 279

  Fly   304 RLPGDKNSPRLLSRLELIEFLRNIYTGPRHTE-QHVTVGMVGYPNVGKSSTINSLMTVKKVSVSA 367
            .......:|  ..:...|:.||..  |..||: :.::||.:|||||||||.||:|.:.|..:|:.
Mouse   280 AFHASLTNP--FGKGAFIQLLRQF--GKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAP 340

  Fly   368 TPGKTKRFQTLFLDKDILLCDCPGLVMPSFVLTKADMLLNGILPIDQMR---DHVPAVNLLCERI 429
            ..|:||.:|.:.|.:.|.|.||||:|.|| ..::.|::|.|::.:::::   ||:.||   .||.
Mouse   341 IAGETKVWQYITLMRRIFLIDCPGVVYPS-EDSETDIVLKGVVQVEKIKAPQDHIGAV---LERA 401

  Fly   430 PRHVLEDKYGIVIAKPLEGEDMERPPHSEELLLAYGYNRGFMTSNGQPDQARSARYVLKDYVNGR 494
            ....:...|.|        |..|   ::|:.|.......|.:...|:||....::.||.|:..||
Mouse   402 KPEYISKTYKI--------ESWE---NAEDFLEKLALRTGKLLKGGEPDMLTVSKMVLNDWQRGR 455

  Fly   495 LLYAMSPPSV---------PQTEYHTFPERQRRVIEESQLPGQQQRAMRINKSTSKELDNQFFSD 550
            :.:.:.||:.         |.:......|..:...||.....:.:|:..|   |.||.:.....|
Mouse   456 IPFFVKPPNAELPTDSQLPPSSPLEVPTETTQNNPEEETTETEVERSDSI---TEKEPEGDCSQD 517

  Fly   551 KPTHAH---VKGRTNFPNVRLANDGSLVAGND 579
            :.:...   .:.|.||..:   |.|...:.:|
Mouse   518 RNSEMQQILARVRQNFGKI---NVGPQFSADD 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns3	NP_001284779.1	RbgA	161..524	CDD:224083	96/375 (26%)
		HSR1_MMR1	164..395	CDD:206750	64/231 (28%)
		p10	<270..312	CDD:177631	4/41 (10%)
		P-loop_NTPase	313..>357	CDD:304359	19/44 (43%)
Gnl2	NP_663527.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33
		NGP1NT	43..174	CDD:400461	27/148 (18%)
		NGP_1	209..365	CDD:206751	61/225 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	462..521		12/61 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	538..595		2/9 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	636..728

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810