Protein Alignment Ns3 and nst-1

DIOPT Version :9

• Sequence 1: NP_001284779.1
• Gene: Ns3 / 31097
• FlyBaseID: FBgn0266284
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_495749.1
• Gene: nst-1 / 174329
• WormBaseID: WBGene00003821
• Length: 556
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 130/573 - (22%)
• Similarity: 242/573 - (42%)
• Gaps: 98/573 - (17%)

  Fly    65 RTAELAGTEFQAEKLNITFVNP---KQRVGLLSKTQEQRMHQKHDEHRDQLKIPRRPKWTKETSA 126
            :.|:..||..:.|| .|:..|.   |:.:.:.::.:.:::..:.:..::..||.|..|......|
 Worm    34 KEAKKNGTTNKKEK-TISVPNSCPFKEEILVQAEQEREKIKVRQEAAKEAAKIHRIEKRKNNLPA 97

  Fly   127 --EELVRAENEAFLDWRRDLALLQEDEEILMTPYEKNLE-FWRQLWRVVERSDVVVQIVDARNPL 188
              |.:|...::...::.:.:|...|.|: ..|..:|.:: :..::.:.||.:||::|::|||:||
 Worm    98 NFESMVAKASKQGTEFDKKVASAAEHEK-FNTLDDKTIKAYASEVRKTVEIADVIIQVLDARDPL 161

  Fly   189 LFRSADLERYVKEVEPSKMNMILVNKSDLLTEEQRRHWAEYFDSEGIRTAFYSATLVEEELKREA 253
            ..||..:|..|  ::..|..::|:||.||:..|..:.|.||...:....||.::|
 Worm   162 GSRSKSVEDQV--LKGGKRLVLLLNKIDLVPRENVQKWLEYLRGQFPTIAFKAST---------- 214

  Fly   254 EECLDSFPEVQQLRRAVEEIKQSLDSVEDALNVIEQKYKTIPETQNDELPRLPGDKNSPRLLSRL 318
                             :|.|.::.....|:            ..|.|..:..|.....::|:
 Worm   215 -----------------QEQKSNIGRFNSAI------------LNNTETSKCVGADIVMKILA-- 248

  Fly   319 ELIEFLRNIYTGPRHTEQHVTVGMVGYPNVGKSSTINSLMTVKKVSVSATPGKTKRFQTLFLDKD 383
               .:.||     :..:..:.||:||:|||||||.||||...|..:|...||.||..|.:.|||:
 Worm   249 ---NYCRN-----KDIKTSIRVGVVGFPNVGKSSVINSLKRRKACNVGNLPGITKEIQEVELDKN 305

  Fly   384 ILLCDCPGLVMPSFV-LTKADMLLNGILPIDQMRDHVPAVNLLCERIPRHVLEDKYGIVIAKPLE 447
            |.|.|.||:::.|.. |...::.|...:.:|.:.|.:..|:.:..|..:..:...|.:.....:
 Worm   306 IRLIDSPGVILVSQKDLDPIEVALKNAIRVDNLLDPIAPVHAILRRCSKETIMLHYNLADFNSV- 369

  Fly   448 GEDMERPPHSEELLLAYGYNRGFMTSNGQPDQARSARYVLKDYVNGRLLYAMSPPS--------- 503
                      ::.|.......|.:....:||...:|:.||.|:..|:|.|...||.
 Worm   370 ----------DQFLAQLARRIGKLRRGARPDVNAAAKRVLNDWNTGKLRYYTHPPEQGTAKEDIV 424

  Fly   504 VP---------QTEYHTFPERQRRVIEESQLPGQQQRAMRINKSTSKELDNQFFSD----KPT-- 553
            ||         :.:.....|.|.:::|  .||.:.......|....::.|::..:|    |.|
 Worm   425 VPAEVVSQFSKEFDIDAIAEEQNQIVE--GLPMESDIIAPHNSDEEEDDDDEMETDVNEKKQTVT 487

  Fly   554 -HAHVKGRTNFPNVRLANDGSLVAGNDPAAKPWRHVKKERREKLRKKFSHLDE 605
             ...|||.|...:..:..:...:.||....|..:...|::::|.:|..:..|:
 Worm   488 SGRKVKGPTKDDDKPVLPESLALEGNVQLNKLIKTAIKKQKKKSKKTANRADK 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns3	NP_001284779.1	RbgA	161..524	CDD:224083	92/382 (24%)
		HSR1_MMR1	164..395	CDD:206750	66/230 (29%)
		p10	<270..312	CDD:177631	6/41 (15%)
		P-loop_NTPase	313..>357	CDD:304359	16/43 (37%)
nst-1	NP_495749.1	GN3L_Grn1	17..84	CDD:285863	8/50 (16%)
		RbgA	140..439	CDD:224083	89/360 (25%)
		Nucleostemin_like	149..314	CDD:206753	63/215 (29%)
		P-loop_NTPase	263..401	CDD:304359	44/148 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810